3 results
The primary objective of this trial is to recommend a dose of Lapatinib in combination with Gemcitabine, Cisplatin and possibly Paclitaxel. In order to achieve this, the study will first determine the maximum tolerated dose (MTD) based on the…
The main question of this study is: *Is selective beta-blocker treatment safe and effective in reducing sympathetic overdrive, thereby improving RV function and remodeling in patients with iPAH?*.In addition to the determination of RVEF, we will…
The purpose of the study is to investigate how safe the compound is and how well the compound is tolerated when it is applied in the form of transdermal patches. The study will also investigate how quickly and to what extent bisoprolol is absorbed…