2 results
Approved WMOCompleted
* To evaluate the safety and tolerability of adding multiple oral doses of HTL0018318 in elderly volunteers taking donepezil at steady state.* To compare the pharmacokinetic profiles of HTL0018318 and donepezil when given alone and in combination at…
Approved WMOCompleted
The objective of this study is to deliver the *proof-of-concept* that locally administered pilocarpine drops are effective in a population of elderly with xerostomia at expense of a minimum of side effects.