3 results
Our primary objective is to investigate the effects of endotoxin-induced systemic inflammation and subsequent development of endotoxin tolerance on the inflammatory response following Fluenz® administration in vivo. To evaluate whether these effects…
- To examine the effects of cytochrome P450 induction by rifampicin on the metabolism and pharmacokinetics of tamoxifen and its metabolites. Induction of cytochrome P450 enzyme expression (including CYP3A4, CYP2C and CYP2D6) by rifampicin will…
- Primary objective is to assess the local tolerability of dry powder hydroxychloroquine via the Cyclops* at different dosages.- Secondary objective is to investigate systemic pharmacokinetic parameters of dry powder hydroxychloroquine via the…