2 results
Approved WMOCompleted
To demonstrate that a dose reduction of 20-33% of CYP3A4 metabolized tyrosine kinase inhibitors in patients expressing the CYP3A4*22 gene (rs35599367 C>T in intron 6) does not result in a lower exposure (Ctrough) than the wildtype group with…
Approved WMOCompleted
Primary objective:* Assess the test-retest repeatability and reproducibility of radioligand [11C]-UCB-J binding.Secondary objective:* Compare the precision and accuracy of PET data analysis using 60 versus 90 minutes of scan data.* Assess group…