6 results
Primary Obejective:To evaluate the preliminary efficacy of 8 consecutive weeks of QBM076 in current or ex-smoking patients with stable COPD with spirometry grades I-III (according to the current GOLD strategy (GOLD 2013).Secondary Objectives:To…
Primary: To characterize the safety and tolerability of PDR001 in combination with LCL161, everolimus, HDM201, QBM076 or panobinostat and to identify recommended doses and schedules for future studies.Secondary: To characterize changes in the immune…
Primary objectivesMeasuring the SARS-CoV-2-specific immune response against SARS-CoV-2 after inoculation with a single-dose Janssen compared to a homologous vaccination regimen with Janssen /Janssen and the comparison of a homologous vaccination…
This translational study focusses on the altered / improved immune response triggered by the addition of radiation to immune checkpoint blockade therapy. The study is investigative in nature.Main study parameters/endpoints:a) Alteration / increase…
Key objective The key objective of the study to determine whether it is necessary to boost the healthy population in autumn. Primary endpoint: The primary endpoint is to determine the fold change in antibody level at day of boost and 28 days after…
Phase I Dose Escalation1.To determine the RP2D in terms of safety and tolerability for:•IV admin of HB-201 in patients with HPV 16+ confirmed HNSCC•IT admin of HB-201 in patients with HPV 16+ confirmed cancers•IV admin of HB-202 in patients with HPV…