5 results
The main objective of this study is to define the optimal dose of fluorescent tracer for intraoperative detection of tumor delineation during breast cancer surgery.
- To evaluate the treatment efficiency by time to progression according to RECIST 1.1
Image guided surgery in sinonasal inverted papilloma by targeting vascular endothelial growth factor
The main objective is to study if the conjugate bevacizumab-IRDye800CW accumulates more in sinonasal inverted papilloma than in normal sinonasal mucosa, with a TBR of *2 as cutoff value.
Primary Objectives• Safety and tolerability• PK of OCA and its conjugates o SD PK Phase: To assess the PK of OCA and its conjugates after a single low dose of OCA on Day 1 and determine subject eligibility for the MD Phase o MD Phase: To assess the…
Primary objectives -To determine whether real-time tumor visualization using targeted fluorescent imaging during breast conserving therapy in breast cancer patients can be achieved intraoperatively and results in adequate assessment of the tumor…