4 results
Approved WMOCompleted
* to describe the safety profile for qW, q2W and q3W regimens. * to determine the Maximum Tolerated Dose (MTD), if achieved (all regimens)* to describe the pharmacokinetics (PK) of single-agent RO6895882. Substudy BP28920/IMGThe study is designed to…
Approved WMOCompleted
To study the effect of TRH on opioid-induced respiratory depression in healthy volunteers.
Approved WMOCompleted
To investigate the effect of food on the PK of a single dose of AZD1775 printed capsules following oral dosing in patients with advanced solid tumours
Approved WMOCompleted
To assess the safety of AZD1775 following oral dosing of the capsule formulation in patients with advanced solid tumours