7 results
* Part A: To investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of increasing doses of YTX-7739 in healthy subjects. * Part B: To study the effect of food on pharmacokinetics of YTX-7739 in a selection of subjects who…
The primary objective of this study is to assess the pharmacokinetics and the effect of food on the pharmacokinetics of the YTX-7739 tablet formulation following single oral doses of 30 mg in HVs and to compare the relative bioavailability of the…
Primary Objective•*To evaluate the relative oral bioavailability of SMV, ODV, and AL-335 when administered as different concept fixed-dose combination (FDC) formulations compared to the single agents when administered together, all under fed…
The study will be performed in 4 parts, Parts A, B, C and D. The purpose of the study is to investigate to what extent single doses of RG2459 are tolerated in healthy volunteers and patients with a hepatitis C infection and to what extent multiple…
The aim of this study is to investigate the effect of ARTISS compared with our standard care on total volume of donor site seroma after harvesting a LD in immediate breast reconstruction. Seroma is diagnosed, when >= 20 mL can be punctuated…
We hypothesized that obliteration of the dead space following mastectomy would significantly reduce seroma formation and therefore seroma related wound complications and patient discomfort (fewer seroma aspirations and fewer check ups in the out…
To investigate the safety, tolerability and pharmacokinetics after multiple daily doses of YTX-7739