6 results
Investigate effect of IF on insulin resistance and possible role acylcarinitin profiles and glycolipids
The primary objective of the study is to evaluate the safety and tolerability of single-dose IV infusion of BIIB033 administered to healthy adult volunteers.Secondary objectives of this study are:* assess the single dose PK profile of BIIB033 *…
1) To assess insulin sensitivity and response in critically ill septic neonates and children. 2) To determine protein balance in septic, critically ill children at baseline and during a Hyperinsulinemic Euglycemic Clamp, while receiving standard or…
To determine whether glucose, lipid and protein metabolism can be accurately measured using stable isotopes in the same patient on two occasions in a 48 hour interval.
Primary: The primary objective of the study is to evaluate the efficacy of BIIB033 in subjects with active relapsing MS when used concurrently with Avonex. Secondary: Secondary objectives of this study in this study population are to assess the…
To identify which brain regions are activated after intranasal application of insulin and how this affects peripheral metabolism.