4 results
Approved WMOCompleted
The primary objective is to compare the antitumor activity of LDK378 versus reference chemotherapy.The key secondary objective is to compare Overall Survival (OS) in patients treated with LDK378 versus reference chemotherapy (pemetrexed or docetaxel…
Approved WMOCompleted
The purpose of the study is to determine how a single administration of rifampicin influences the uptake and breakdown of ACT-246475. Furthermore, the safety and tolerability of ACT-246475 when administered after administration of rifampicin, will…
Approved WMORecruiting
To evaluate the efficacy based on the histological response
Approved WMOCompleted
The primary objective is to compare the antitumor activity of LDK378 versus reference chemotherapy