6 results
The primary objectives of this study are to evaluate the safety of 12 weeks of treatment with ABT-450/r/ABT-267 and ABT-333 with and without RBV, and to show the non-inferiority in SVR12 rates (the percentage of subjects achieving a 12-week…
To test the impact of the addition of axitinib to standard chemotherapy treatment on histology samples
To measure the effect of domperidone and omeprazole on reflux-time, duration, and symptoms of GERD
The primary objectives of this study are to compare the percentage of subjects achieving SVR12 (HCV RNA < lower limit of quantification [LLOQ] 12 weeks following treatment) of 12 weeks of treatment with ABT-450/r/ABT-267 and ABT-333 co-…
To assess the prevalence of QT-prolongation in patients who are prescribed domperidone as part of usual care, and to assess potential risk factors for that QT-prolongation.
Primary: Evaluate the efficacy of patient-derived tumor organoids to successfully allocate patients for treatment with specific targeted agents.Secondary: Characterize safety and tolerability per experimental treatment regimen.