7 results
To determine the toxicity of adding chloroquine in escalating doses in patients with small cell lung cancer to standard therapy.
To determine the relation between tumor tissue phosphoproteomic profiles and progression-free survival (PFS) in patients with advanced RCC
To determine the toxicity of adding chloroquine in escalating doses in patients with small cell lung cancer to standard therapy.
To investigate efficacy of neoadjuvant axitinib and avelumab in patients with localized renal cell carcinoma with moderate to high risk of recurrence .
Primary objective- To measure the effect of sapropterin on diurnal and day to day variations of blood phenylalanine concentrations.Secondary objective- To measure the effect of sapropterin on diurnal and day to day variations of blood tyrosine…
Sub-study APhase 1b:To assess the DLT rate and estimate the MTD of sasanlimab in combination with encorafenib and binimetinib to determine the RP2D for the combination. Phase 2:To assess the durable ORR of sasanlimab in combination with encorafenib…
Primary Objective: To evaluate the effect of solriamfetol on cognitive functioning using an objective measurement. Secondary Objective:To evaluate the effect of solriamfetol on cognitive functioning using a subjective endpoint