5 results
To determine if there is a difference in the pharmacokinetics of low-dose cisplatin with and without prehydration.
Our first goal is collecting high quality raw EEG waves, - measured simultaneously on multiple locations of the brain - during a pharmacological reproducible anesthesia. The goal is to observe EEG patterns that allow the development of technology to…
Primary Objectives: To investigate the pharmacokinetic interaction of elexacaftor/tezacaftor/ivacaftor and tacrolimus in adult CF patients using tacrolimus after renal or liver transplantation by:- quantitating the effect of elexacaftor/tezacaftor/…
Primair eindpunt:Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy in Subjects With Cystic Fibrosis (CF) Who Are Homozygous or Heterozygous for the F508del Mutation.Secundair eindpunt:Evaluate the long-term efficacy of VX-…
Primary objective (Parts A and B):To evaluate the long-term safety and tolerability of VX-445/TEZ/IVA in subjects with CF who are heterozygous for the F508del mutation and a gating (F/G) or residual function (F/RF) mutation.Secondary objectives (…