6 results
The objective of the study is to observe the effect of olanzapineat a dose of 10 mg daily for 14 days when given with/without topiramaat at a dose of 25 and 50 mg twice daily on bodyweight in healthy male subjects. In addition the effect of…
The purpose of the study is to investigate how well LY2165766 is tolerated, and to investigate whether LY2165766 administration is associated with body weight gain in comparison to placebo. Olanzapine is included in this study as a positive control…
We aim to prevent or reverse developmental regression in patients with Kleefstra syndrome. We hypothesise that the regression we observed is the result of a psychotic disorder, which isnot properly recognised by clinicians and often not treated…
Primary objectiveEvaluation of [18F]MC225 to measure the P-glycoprotein function in Alzheimer*s disease, Mild Cognitive Impairment and Parkinson*s disease. Secondary objectives1. Evaluation of blood-brain barrier integrity using [18F]MC225 and MRI…
The main objective of this study is to investigate gender differences in P-gp function at the blood brain barrier, in order to gain further insight into the impact of these differences on the action of pharmaceuticals (antidepressants and…
Main objective- to investigate the effect of alfacalcidol on the treatment of secondary hyperparathyroidism in patients after RYGB Secondary objectives: - to investigate bone turnover and changes in BMD in relation to secondary hyperparathyroidism…