4 results
To anwer the question: Is the elevation of energy expenditure and mitochondrial uncoupling smaller in obese than in lean subjects after mild cold exposure and what is the role of the sympathetic nervous system?
Primary Objective: Major amputation rate after 12-months of follow-upSecondary Objectives: - Amputation-free survival- Health-related quality of life- Complete wound healing- Pain scores- Need for additional (vascular) interventions- Cost-…
The aim of the POLO study is to evaluate pharmacokinetics and safety of a single-dose of dolutegravir in patients with severe hepatic impairment (Child-Pugh score * 10) and compare these to matched controls.
To investigate the therapeutic efficacy and feasibility of hyperbaric oxygen (HBO) in addition to standard wound care in patients with pyoderma gangrenosum wounds.