70 results
A model based on the combination of clinical prognostic factors and features extracted from tumor contours from CTPET has a high accuracy to predict pathologic complete response after chemoradiotherapy in locally advanced rectal cancer.
To study's primary objective is to establish the effectiveness of a low-threshold guided self-help intervention targeted at improving one's self image in people with anxiety and/or depressive symptoms and low self esteem. We expect to find…
Otosclerosis is an isolated ear disorder which can cause hearing and balance impairment. The cause of these symptoms is a disturbed bone metabolism confined to the area of the otic pit, the embryologic predecessor of the inner ear. Most patients…
1. Cooling to 34, 34.5 or 35°C by means of a surface cooling device, started within 4.5 hours after the onset of acute ischaemic stroke and maintained for 24 hours in awake patients on a stroke unit is safe; 2. In awake patients with ischaemic…
The nephrotoxicity caused by cisplatin is of great concern both in that it is dose-limiting and can be detrimental to the patient. Much work has been done to reduce or prevent this damage to renal cells, however to date the best approach has reduced…
Modern dressings containing silver are more effective than topical antibiotic treatment for healing of PEG-site infections.
1. Cancer survivors who received the high-intensity exercise program will have significantly higher muscle strength, cardiopulmonary function, and health-related quality of life after 12 weeks intervention compared to cancer survivors who received…
A positive effect of a Growing Up Milk with added prebiotics or prebiotics and LCPUFA on the intestinal microbiota of toddlers.
Chronic chilblains is a common disease causing major restrictions in daily life, nevertheless little is known about treatment. In a literature search, we found thin evidence of three interventions: fluocinolone cream, nifedipine and vitamin D3.…
The objective of the study is to identify all subjective and objective outcome measurements which have been used in TMC-OA trials and classify them according to the OMERACT core set and the ICF categories.
radiological factors for DRUJ instability may account for DRUJ instability in patients after a consolidated distal radius fracture with negative influence on outcome
In patients with WAD the strength of the relationship between self reported disability and work capacity is weak to moderate (correlation coefficient between r=0.25 and r=0.75). Work capacity and performance can be predicted with the help of…
The accumulation of, in both serum and tissue AGEs, will be increased in diabetic pregnancies.
The immune response of diabetic pregnancies is altered in comparison to healthy pregnant women.
In this study we will investigate the progression of IF/TA in protocol biopsies in a cohort of renal transplants, with a steroid sparing TAC-based immunosuppressive regimen in combination with either sirolimus (SRL) or mycophenolate mofetil (MMF),…
One of the challenges in paediatric anaesthesia is to minimize distress for children in the operating room environment and to facilitate a smooth induction of anaesthesia. Pre-anaesthetic medication reduces the risk of adverse psychological and…
Major depressive disorder (MDD) is projected to rank second on a list of 15 major diseases in terms of burden and is highly recurrent in nature. Accordingly, efforts to reduce the disabling effects of this chronic condition should shift to…
We hypothesize that transfusing red cells with a storage time of 2 to 8 days reduces the incidence of nosocomial pneumonia in ICU patients.
We have stated the hypothesis that a reduction in sublingual microvascular perfusion following esophagectomy is not only a symptom of a generalized inflammatory stress response but can also be predictive for the development of postoperative…
Pulse oximetry is a non-invasive method allowing monitoring of the oxygen saturation of a patient. For many years now, it has been used in secondary care with great success. Recently, it is noticed that pulse oximetry is used more often in the…