28 results
Primary Objective: To assess the hemodynamical effects of administration of AS in FGR fetuses and to compare these effects with those that occur in appropriate for gestational age (AGA) fetuses. Secondary Objective(s): To investigate the effect of…
Objective: To show the protective value and to measure cost effectiveness of higher Ig dosing on progression of lung disease in PAD.
Measuring tFUS-dependent changes in behaviour (in our target tasks) when targeting deep brain regions [Behavioral Objective]
The main aim is to study whether fNIRS can measure cortical activation during pelvic floor muscle contraction and to study whether it is a reliable non-invasive alternative to invasive pelvic floor EMG in order to provide biofeedback during pelvic…
There are three main objectives in this study. The first objective is to compare online and offline CSO based on their psychopathic traits, narcissism and other personality dysfunctions. The second objective is to further investigate the more…
The objective of the proposed study is to determine the effectiveness, safety and cost-effectiveness of a strategy of cefuroxime combined with short course treatment with aminoglycosides compared to a strategy of ceftriaxone monotherapy in patients…
To assess the effect of treatment with 100 mg of FAB122 (edaravone) on disease progression in patients with ALS.
The main objective of study 20190530 is to estimate the efficacy of Apremilast compared to placebo in the treatment of oral ulcers in pediatric subjects from 2 to < 18 years of age with oral ulcers associated with BD through week 12. See…
Study A: Validation of productive infection of RSV CHIM Study B: Effectiveness and immunogenicity of local administration of palivizumab on prevention of experimental RSV infection
Primary objective:To assess whether the state of premature immune aging (senescent CD8+ T cells) predicts treatment response to physical endurance intervention therapy in depressed patients. We will compare the mood-beneficial effects of physical…
This study will evaluate the efficacy and safety of multiple therapies that are selected using somatic alterations and potential predictive biomarkers identified via NGS assays in patients with solid tumors:
Primary:• Compare progression-free survival (PFS) as assessed by the Independent Review Committee (IRC) per Response Evaluation Criteriain Solid Tumors (RECIST) Version (v) 1.1 in ociperlimab plus tislelizumab (Arm A) versus Durvalumab (Arm C) among…
The primary objective of this study is:* To assess the safety and tolerability of TPN-101 in patients with C9ORF72 ALS/FTDThe exploratory objectives of this study are:* To assess the concentrations of TPN-101 in plasma and cerebrospinal fluid (CSF…
To evaluate participant satisfaction and effectiveness of the CoolSculpting Elite System using CoolSculpting Elite applicators for non-invasive subcutaneous fat reduction of the abdomen and flanks, upper arms, inner thighs, outer thighs and…
Primary:• To evaluate AD-specific, neuroinflammatory, neurotrophic and neurodegenerative biomarkers and safety of 3 intrathecal (IT) administrations of NurOwn® (MSC-NTF cells) given at two monthly intervals to participants with prodromal to mild…
To evaluate the efficacy of OT-101 Ophthalmic Solution in treating the progression of myopia in pediatric subjects following 3 years of treatment.To evaluate the safety and tolerability of OT-101 Ophthalmic Solution in pediatric subjects with myopia…
Primary Objective:To evaluate the safety and tolerability of FL-101 as monotherapy and in combination with nivolumabTimepoint of evaluation of primary objective: From first dose to 3 months after surgerySecondary Efficacy Objectives1. Cohort 1: To…
To assess the course of microcirculatory disturbances during ECMO. Furthermore, we will evaluate the effect of implementation of ROTEM in terms of thrombotic and hemorrhagic events and the use of blood products in patients on ECMO.
Study of a novel implantable device to generate an autologous vascular graft for hemodialysis access
The objective of the study is to assess the use of the Tissue Capsule for AV grafting in renal failure patients and testing these AV grafts for hemodialysis access.
The objective of this study is to assess the added value of polygenic risk scoring in psychiatric genetic counseling for patients with serious mental illness (SMI) and their family members. The secondary objective of this study is to explore…