39 results
The purpose of this study is to see if we can predict which patients with CTS are eligible for an injection, and which should be directly referred to a surgeon. This to shorten the period of the patient's symptoms and to save healthcare costs.
The main objective of this study is to evaluate the long term results (minimum of 10 years) of arthroscopic debridement of the rotator cuff in the treatment of partial rotator cuff ruptures.
Primary:The purpose of this study is to evaluate the safety, tolerability, orally administered LMI070 in patients with Type 1 SMA.pharmacokinetics (PK), pharmacodynamics (PD) and efficacy; and to estimate the Maximum Tolerated Dose (MTD) and optimal…
The primary objective of the PASSENGER study is to investigate any relationship between changes in SonR1 augmentation and a change in patients* exercise capacity as assessed by the 6 Minute Walk Test.
The main objective is assessment of safety and feasibility of intravenous administration of autologous, in vitro expanded, mesenchymal stem cells in patients with pulmonary arterial hypertension due to systemic sclerosis. The secondary objective is…
Primary Objective: To study known heartfailure biomarkers (proteomics, microRNAs and metabolomics) for the detection and prognosis of cardiotoxicity in patients receiving antineoplastic therapy, and to discover predictive biomarker (values). In the…
This is a post-marketing study to further assess the safety and efficacy of the InSpace* device implantation in comparison to surgical repair of full thickness MRCT . The efficacy will be assessed by comparing the pre- and post- operative shoulder…
The primary objective of the pilot study is to optimise the design of the large cohort study and test the logistics and course of measurement. Furthermore, the pilot study allows us to assess and adapt the burden of the measurements for the children…
to investigate whether the levels of a panel of biomarkers in dried blood spots can be used as a disease severity measurement tool in patients with AD, treated with topical steroids.
The main goals of this study1) To determine the prevalence of BE among first degree relatives of index patients in families that fulfil criteria for familial BE/adenocarcinoma of the GEJ2) Collect tissues of the index patients and all first degree…
To elucidate the changes in the timing of sleep and waking in different chronotypes (e.g. *owls* vs. *larks*) with at least 2 hours of social jetlag exposed to short wavelength (blue) light in the mornings upon awakening using Philips goLITE blu…
The COMBO HEALING evaluates the long term healing pattern of the Abluminal Sirolimus Coated Bio-Engineered Stent (Combo Bio-Engineered Sirolimus Eluting Stent) in routine clinical practice. The primary objective of the study is to the asses the long…
To assess the efficacy of nab-paclitaxel administered intravenously (IV) on Days 8and 15 with epigenetic modifying therapy of CC-486 once daily (QD) on Days 1 to14 every 21 days, and nab-paclitaxel monotherapy administered IV on Days 1 and 8every 21…
To determine whether the attenuated salivary cortisol response in children with asthma can be explained by the maintenance use of inhaled cortiocosteroids, the chronic inflammatory disease, or the attenuated exercise capacity.
In this study we will explore changes in the hepatic function after stimulation of hepatic cells with an oral food challenge, the **hepatocyte reserve capacity**. Moreover, we will explore potential differences in the hepatocyte reserve capacity…
Primary: To evaluate local tumour control by using HIFU technology.Secondary: To evaluate treatment toxicity, disease progression and QoL.
The objective of the study is to analyse flow pattern, especially individual variation, and the extend of voiding symtoms in young females and
The primary aim of the present study is to investigate whether the Mindset Reconditioning program can safely be applied in patients with CRPS. A secondary aim is to assess the efficacy of Mindset Reconditioning before the preparation of a randomized…
Primary:The primary objective of this study is to determine whether DMF taken over 12 months is effective in reducing MS-related fatigue, as measured by mean changes in the Fatigue Scale for Motor and Cognitive Functions (FSMC), in subjects with…
To compare the accuracy of syndesmotic reduction on an axial CT-scan postoperatively (reflecting syndesmotic malreduction) after anatomical open reduction and fixation of the posterior malleolar fragment versus no fixation of the posterior fragment…