52 results
The purpose of this clinical study is to provide confirmation of the clinical safety and performance of the CINCOR* System in patients at risk of developing CIN who are undergoing interventional percutaneous coronary procedures.Further, the data…
Primary goal:To investigate whether specific plaque characteristics are associated with ischemic lesions, especially (clinically silent) cerebral micro-infarcts, we will perform preoperative high resolution 3 and 7 Tesla MR plaque imaging in…
Primary Objective: Mapping the consequences of a congenital monokidney on kidney function for children with MCKD.Secondary Objective(s): - Giving recommendations about follow-up for children treated with nephrectomy for MCKD.- Defining better blood…
ObjectiveInventory of the support and willingness of the visitors of the temples to participate. This study should be beneficiary in the development of a preventive program, focusing on depression. The primary outcome of this randomised trial is:…
Primary objective: to compare changes in endothelial function in patients with obesity related hypertension after 8 weeks of treatment with aliskiren, moxonidine and HCTZ.Secondary objectives: to compare changes in the following parameters in…
(1) How accurately do the TVS-CMD items reflect clinically relevant symptoms? (2) What is the concurrent and discriminant validity of the TVS-CMD? (3) How can the scoring system of the TVS-CMD be optimised?
Change from baseline in regional cerebral blood flow in response to various visual stimuli ascertained by Positron Emission Tomography scan after 8 weeks of flibanserin 100 mg treatment.
To identify intraarticular parameters related to the initiation and course of development of articular cartilage lesions after knee trauma.
2.1 Primary objectiveTo compare the wear rate 24 months after THA of HXLPE stabilized with vitamin E versus conventional UHMWPE for total joint arthroplasty.2.2 Secondary objectives1. To compare the wear rate at 3,12 and 24 months after THA between…
1. Is KJD clinically non-inferior to current surgical techniques (HTO and TKP)?2. Is KJD superior to HTO in actual structural repair of cartilage?3. Is KJD cost-effective in the long-term compared to HTO and TKP?
The major research objective is to prove that the consumption of plant stanol ester enriched yogurts can improve immune function in vivo in asthma patients
To compare an unexplained chronic fatigue group and a healthy control group on: 1) immune parameters (hs-CRP), 2) several subjective (self report) measures of non-specific symptoms of immune activity, 3) several objective measures of non-specific…
The aim of the study is to evaluate the safety of the Flex catheter and the effect of the renal denervation on blood pressure.
The first objective of this study is whether DCS addition to exposure therapy enhances symptom reduction in PD+AGO. The second objective of the study is to establish the optimal timing of administration of D-cycloserine (directly pre- or post…
Primary Objectives:1. To compare the magnitude of baseline (or intrinsic) platelet reactivity between T2DM patients and healthy volunteers using multiple platelet function assays 2. To compare the magnitude of baseline (or intrinsic) platelet…
Investigate the effects of levocetirizine, diphenhydramine and placebo on cognitive and psychomotor functioning during controlled simulated diving in a recompression chamber in professional navy divers at 10 mt (2 bar) and 30 mt (4 bar).
To determine safety and efficacy of oocyte vitrification.
This pilot clinical trial has been designed to evaluate the safety and performance of the INSTRUCT scaffold, and to collect preliminary efficacy data
Our goal is to evaluate if this onsite assessment and aspiration during punction reduces inadequacy of specimens and see if onsite assessment by the aspirator is performed accurately after a brief instruction by a cytopathologist. Primary Objective…
The primary objective is to study whether treatment with the mTOR inhibitor Everolimus results in an objectable change in phosphorylation of the selected downstream effectors 4eBP1 and p70S6K in human prostate cancer biopsies. A secondary objective…