59 results
To determine exercised-induced bronchoconstriction with an objective and standardized exercise test for infants and young children (3-6 years); to compare resistance and compliance in wheezy children and healthy children before and after exercise-…
Analyze the correlation between change in EELV with change in MIF¬50
Primary ObjectivesThe primary objective is to assess the efficacy (primarily through time to relapse) of long-acting injectable (LAI) paliperidone palmitate compared to treatment as usual with orally administered antipsychotics in monotherapy over…
To evaluate the effects of tDCS on modulating and stydying frontal brain asymmetry.
To evaluate the safety and activity of BB3 compared to placebo in improving renal function in the immediate post-transplant period in patients who have received a DCD kidney transplantation.
To assess whether pacing from the right ventricular outflow tract, the right ventricular apex or combined pacing shows difference in right and left ventricular ejection fraction and asynchrony.
Research Goals: During the pre-study several clues indicated that hunger isnot increased when tubefeeding is administered. This couldpoint to a lower ghrelin production during tubefeeding,indicating that tubefeeding is the next step in…
The first aim is to determine the amount of nocturnal reflux (reflux time / 24 h) in obese subjects compared to normal weight subjects. Secondary objectives are to identify possible mechanisms which cause nocturnal reflux in this patient group and…
Main objective: Contributing to the debate on the necessity of PPC in episodic memory by support of patient data. Secondary objective: Exploring the episodic memory theorem and developing a more sensitive (neuropsychological) research tool usable in…
To investigate the effect of AMG 785 compared to placebo on time to radiographic healing of fresh tibial diaphyseal fractures.
Objective: Main object Does warming of oxaliplatin, during the two hours infusion period, reduces the acute peripheral neuropathy complaints of patients with a colo-rectal tumor more than 50% in comparison with the standard treatment?Secondary…
1) To investigate the relative contribution of different neurocognitive dysfunctions toADHD.2) To identify potential baseline EEG/MRI markers of different neurocognitive functions in ADHD children and healthy controls.
: The primary objective of this study is to demonstrate non-inferiority by pharmacodynamic (PD) analysis of the prasugrel 5-mg maintenance dose (MD) in aspirin-treated subjects >=75 years of age with stable coronary artery disease (CAD)…
Testosterone, cortisol and estradiol are known to influence information transfer in the brain, the interrelationships between steroid hormones, brain communication and social aggression have never been studied directly.The present study aims to…
Testing nerve stimulation as a preventive measure to reduce the incidence of PONV.
1) To assess insulin sensitivity and response in critically ill septic neonates and children. 2) To determine protein balance in septic, critically ill children at baseline and during a Hyperinsulinemic Euglycemic Clamp, while receiving standard or…
Improve the quality of red blood cells used for cardiopulmonary bypass for neonates and infants with a bodyweight smaller then 10 Kg.
The aim of this study is to identify predictive factors for the outcome of gastro-esophageal reflux disease after gastric banding. Another aim is to identify predictive factors for the development of dysphagia.
Primary Objective: 1) To charaterize microbleeds and microinfarcts at 7T, and compare their prevalence in people with and without diabetes, with or without cognitive impairmentSecondary Objective(s): 2) To assess the relevance of the lesions in the…
Primary Objective: 1) To compare the prevalence en number of microbleeds at 7T between older people with and without DM2, and to relate the lesions to cognitive performanceSecondary Objective(s): 1) To characterize cerebral microinfarcts at 7T and…