47 results
In the current proposal we hypothesize that vulnerability to stress is a non-specific risk factor for developing either schizophrenia or MDD. Increased stress sensitivity is hypothesized to be related to reduced prefrontal functioning, leading to…
The objective of this observational study is the safe introduction of clinical applied IVM in The Netherlands. During this study, the number and quality of the oocytes and embryos will be studied as well as pregnancy development. Emphasis will be on…
Goal of the study is to establish evidence on cognitive biases in a high risk population and on the longitudinal impact of such biases. We hypothesize that CPAD*s show biases in their information processing when compared to control children. We…
The aim of this study is to investigate whether DWIBS may be an appropriate technique for colorectal cancer screening.
Study ObjectiveTo determine whether alprazolam, a registered anxiolytic non-selective benzodiazepine, can reduce the autonomic temperature increase induced with social stress in healthy men. Secondary objectives are to determine whether alprazolam…
To test if viewing a medical consultation on video leads to comparable psychological and physiological responses to the communication as being a patient in that consultation.
1. How functions the dopaminergic neurotransmission in adult patients with VCFS who are functioning on an intellectual level of moderate to severe impairment (IQ < 55) by a) a strong cognitive decline or b) a premorbid level of functioning.2…
We would like to investigate the efficiacy of the treatment of Trigger Fingers by means of a reliable, randomised, controlled, prospective multi-center trial at a large-scale with a long term follow-up. After completion of the trial we will be able…
To scrutinize the role of OT in human social-emotional behaviour and gain insight in the neurobiological mechanism by which the peptide exert their effects.
To determine the reliability and feasibility of the Nanoduct sweat test system compared to the gold standard tests QPIT and Macroduct.
This study is designed as a prospective randomized single blinded trial to evaluate the difference in functional outcome after treatment with tape versus semi-rigid ankle support (brace) for grade II and III acute lateral ankle ligament injuries.
This is a mulricenter phase II study examining the feasability and efficacy of this approach. Subjects will receive by intraveneus infusion a dose of MSC (aiming for 2 x 106/kg or highest avialable dose)
The objective of this study is to prove that a single injection of PRP in the COE decreases the pain and duration of the condition in patients with chronic lateral epicondylitis compared to injection with lidocaine and corticosteroids.The specific…
Objective is to compare the two groups whether the pain scores are at least the same. Also will be noticed if the incidence of side effects of morphine intrathecal are less (e.g. itching, nausea and/ or vomiting and urine retention, although this is…
1) Study the chemopreventive potential of 5-ASA and UDCA in UC by evaluating the effect of treatment with these agents on ACF number, size and rate of dysplasia. 2) Gain mechanistic insight into the chemopreventive properties of 5-ASA and UDCA by…
Analyze the protective effect of levocetirizine (LEV), through the direct antagonism of airway H1 receptors and the inhibition of the release or production of other inflammatory mediators, against exercise induced airway obstruction.
Gain insight into the mechanism underlying enhanced mechanoperception of the stomach and duodenal chemoperception in response to fat in patients with functional dyspepsia.
The primary objective of the study is to demonstrate safety and efficacy of the ALIMAXX-B* covered biliary stent.The secondary objective of the study is to evaluate technical success of stent placement, , re-interventions and time to occlusion.
This pilot study aims to investigate sexual wellbeing, sexual functioning and sexual health care need within four groups of patients with major illness (COPD patients, gynaecological patients, pelvic care patients, and patients with depressive…
The primary objective of the study is to evaluate whether a probabilistic diagnostic approach can replace an approach where the indication for testing for tubal pathology is made with measurement of CAT.