423 results
To investigate the effect of the two test products compared to the effect of the control product in infants delivered by Caesarian Section on the total bifidobacteria count of the gut microbiota.
Intensive counselling from a practice nurse in combination with varenicline (intervention group) will be significantly more effective in smoking cessation than a short quit smoking advice from a general practitioner in combination with varenicline (…
1. Cost-effectiveness: Subcutaneous immunotherapy (SCIT) with tree pollen (TP), grass pollen (GP), house dust mites (HDM) or combinations is cost-effective compared to usual care (UC) only. 2. Clinical effectiveness: SCIT with more than one allergen…
Parents will improve their communication- and education skills about alcohol-, tobacco-, and cannabis use.
Inappropriate aggressive behavior poses a great burden on society and is the main reason for referral to a forensic psychiatric setting. Although behavioral therapy like Aggression Replacement Training (ART) has been shown to be effective in the…
Our hypothesis is that laparoscopic incisional hernia repair comes with a significant shorter hospital stay compared to open incisional hernia repair.
1. What are the normoxic ventilation parameters and systolic PAP in MH patients? 2. What is the influence of hypoxia on the systolic PAP on MH patients?
Multiple observational and animal studies suggest a therapeutic effect of bilirubin in various diseases. To verify this suggestion, intervention studies with experimental hyperbilirubinemia are needed. The current study explores the applicability of…
In patients with irreversible corneal endothelial failure, corneal transplantation is the only effective treatment. Currently, the predominant transplantation technique for patients with corneal endothelial disease is Descemet Stripping Automated…
The purpose of our study is to compare the clinical effectiveness and cost-effectiveness of two treatment strategies of intermittent claudication (IC) due to an iliac artery obstruction: to start with supervised exercise therapy (SET) and deferred…
Training staff of severe mentally ill patients in stimulating a healthier lifestyle (more exercise, a healthier diet) of their patients will improve patients' metabolic health, decrease depressive symptoms and improve quality of life, at…
Red pepper might prevent reduction of energy expenditure and elevation of hunger as a result of energy intake restriction.
1. The primary research inquiry being raised concerns anaesthesia related causes: Is it possible that adapting an amount of Sevoflurane, from 1 MAC (minimum alveolar concentration) (2,5 vol%) to ½ MAC (1,25 vol%) in an MRI scan can reduce the…
To determine the epidemiology, diagnosis and prognosis of enterovirus (EV) and parechovirus (HPeV) infection in Dutch children. Hypotheses: 1. EVs are one of the most important viral agents of infection in Dutch children; 2. EVs are the major cause…
The self-help intervention Happy@Work will reduce symptoms of depression. The self-help intervention Happy@Work will be cost effective.
The objective is to investigate the patterns and processes of change in Acceptance-Based Behavioural Therapy (ABBT; Acceptance & Commitment Therapy + mindfulness) with chronic pain patients having high levels of psychological flexibility.…
1. Measure DNIC and offset analgesia in neuropathic pain patients; 2. Compare DNIC and offset analgesia in chronic pain patients with DNIC and offset analgesia in healthy volunteers; 3. Assess the effect of oral tapentadol on DNIC and offset…
Increased cardiac sympathetic activity is highly prevalent among patienst with chronic heart failure. The increased cardiac sympathetic activity as assessed with 123I-metaiodobenzylguanidine (MIBG) is a usefull tool to discriminate responders (i.e.…
The investigational formula will be equivalent to the control formula with regard to the postprandial blood lipid parameters.
Acetaminophen is effective in treating self-reported sleep problems, in particular insomnia.