2793 results
There might be discrepancies in number and type of Cancer Predisposition Syndrome diagnoses between the genotype first and the phenotype first approach.
The primary objective of this study is to evaluate the effect of surgical correction of pes equinovarus deformity compared to conservative treatment on personalized goal attainment. In addition, we will evaluate the effect of surgical correction of…
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
The primary objective is to examine whether changes over time in monitoring measures of cognition and behavior are associated with functional outcomes in pediatric oncology groups. Additional objectives are to examine trajectories, risk factors, and…
Core:1. Quantify vigilance using a portable task battery three times daily during 7 days while subjects are outside the hospital 1.1 Comparing narcoleptic patients to controls 1.2 Comparing narcoleptic patients before and after treatment with sodium…
PurposeThe aim of this study is to gain insight on an empirical basis into the concept of unbearable suffering in situations where a request for EAS is made from the point of view of the patient, the treating physician, and the consulted doctor and…
The primary objective of this study is to define differences in the inflammatory response, coagulation, and fibrinolysis in CABG patients with either MECC or conventional CPB.
The main research questions are:1a. What are the functional status on all levels of ICF and quality of life of adults with DMD?1b. What are determinants of functional status and quality of life?2a. What are burden of care and quality of life of…
The aim of the present study is to develop a Dutch version of the Pediatric Inventory for Parents and to examine its psychometric properties (test-retest reliability and content validity) in parents of pediatric cancer patients and parents of…
To investigate the correlation between androstenedion in saliva and serum in all patients that have a request for androstenedion in serum.To collect age related reference ranges for healthy children on three different time points.
To investigate whether cough measurements by means of VAS (0-100 points) after 6 months (+/- 6 points) in patients with chronic cough who are diagnosed and treated by a nurse practitioner outpatient clinic are equal to an outpatient clinic leaded by…
Engelse tekst volgt indien onderzoeksvoorstel definitief moet worden voorgelegd aan de METC (in overleg met mevrouw Lilian Damen).
In the proposed experiment we expect to find a similar functional segregation within prefrontal and premotor cortical regions when a free choice option is introduced.
The objective of this study is to generate knowledge about factors related to culture, that hinder the use of rehabilitation care. This follow-up study focuses on patients of non-Netherlands origin that are not any more under treatment, as they have…
Identification of genetic risk factors for development of type 2 diabetes, diabetes related diseases and complications. Furthermore the examination of the relationship between genetic variation, biochemical factors, environmental factors (obesity…
Objectives1. Determine efficacy of adalimumab as the first biologic agent or after previous use of other anti-TNF blocking agent. Efficacy will be evaluated by means of the ASAS 20% response criteria.2. Determine the efficacy of adalimumab on…
The proposed project focuses on: a) implementation of an improved, standardized method for performing quantitative nailfold capillaroscopy to visualize morphological patterns and evaluate its diagnostic use in patients with (possible) CTD and…
The aim of the present study is to investigate: 1) the relationships among different cognitive measures, and 2) the specific relationship of these measures with PTSD symptoms.
2.1 Primary objectives Primary objective is scientific research to study the additional effect of bevacizumab on hypoxia related parameters. 2.2 Secondary objectives a) To compare the efficacy of bevacizumab with pre-treatment obtained values of…
Is SV2A expression in surgically removed tumour and tumour-surrounding tissue of glioma patients suffering from epilepsy correlated with their clinical response to levetiracetam?