1559 results
The primary objective is to compare the effectivity of buprenorphine/naloxone and methadone on self-reported opioid misuse. Secondary objectives include comparing the effects on pain, well-being, functioning, and medication use.
Succes-rate of discontinuation is higher with more gradual tapering of paroxetine or venlafaxine
The primary objective is to examine whether changes over time in monitoring measures of cognition and behavior are associated with functional outcomes in pediatric oncology groups. Additional objectives are to examine trajectories, risk factors, and…
To assess the PK/PD relationship of prednisolone regarding toxicity as clinical outcome in paediatric patients with autoimmune or autoinflammatory diseases
To investigate the pharmacokinetic profile of magistrally compounded CDCA capsules.
Tones vs. neutral self-voice (EEG experiment 1 in Session 3; Pinheiro et al., 2018): a) no effect of HP on N100 suppression for self- and externally generated tones as we would expect alterations in sensory feedback only with regards to one’s own…
The main objective is to study the effect of a nutritional intervention on white matter integrity at the corrected age of three months in infants born at a gestational age <30+0 weeks. Secondary objectives of the study are to determine the…
We hypothesize that the risk of any congenital abnormality in fetuses with an early increased NT that normalizes, will be lower than those with persistent increased NT after 11 weeks of gestation.
The aim of this study is to demonstrate that a single dose of rabies vaccine can induce an equally rapid and adequate anamnestic antibody response as 3-dose PrEP to revaccination five years later.
The experimental treatment (game-supported TPM training) will contribute to a more effective generalisation of compensatory strategies to untrained tasks as compared to the active control group (CogniPlus training).
We hypothesise that patients in the intervention group will show a reduction in sedentary time of at least 60 minutes per day after the cardiac rehabilitation program, compared to a reduction of maximally 30 minutes per day in the control group.
The primary objective of this study is to evaluate the effect of surgical correction of pes equinovarus deformity compared to conservative treatment on personalized goal attainment. In addition, we will evaluate the effect of surgical correction of…
Primary Objective: 1. What is the difference in effectiveness of Early Time-restricted Eating (eTRE) in glycaemic regulation when compared to isocaloric continues caloric restriction (CCR) after one year in overweight adults with type 2 diabetes?…
We hypothesize that the T2T strategy is superior compared to the T2S in retaining gout remission and is also more cost-effective.
To investigate the effect of various dietary interventions and co-administration of subcutaneous semaglutide on the pharmacokinetics of alectinib in NSCLC patients.
We hypothesize that implementation of ambulatory cPNB for postoperative analgesia in lower limb surgery will be non-inferior regarding patient-reported overall benefit of analgesia, when compared to standard care for pain control using sPNB and…
Primary objectives: 1. Assess the feasibility of FMT in PD patients. 2. Assess the safety of FMT in PD patients. Secondary objectives: 1. Explore whether FMT leads to alterations in motor complications (fluctuations or dyskinesias) and…
MOCA using Flebogrif is not inferior to EVLA for the treatment of GSV insufficiency.
To demonstrate superiority of left ventricular septal pacing over right ventricular pacing and to investigate the additional effect of capturing the left bundle branch in left ventricular septal pacing (LVsP). This will be done by studying…
The primary aim of the study is to improve the oral cleanliness of young high caries active children by a HAPA-based intervention to improve the brushing behaviour of parents in their children. Therefore, the effect of the HAPA-based intervention is…