1533 results
To assess the PK/PD relationship of prednisolone as either prophylaxis or therapy of GVHD in children after HCT.
Extracellular vesicles (EVs) in plasma can be used as a biomarker for stroke diagnosis, thereby discriminating between ischemic and hemorrhagic stroke.
Postoperative NRS pain scores in the breast after BCS are lower in women who receive a preoperative PECS II block than in women who receive a sham block.
We hypothesize that functional Near Infrared Spectroscopy (fNIRS), eye-tracking, Indirect Calorimetry (IC), the BOD POD, and Bio-Impedance Analysis (BIA) are feasible outcome measures for children with Angelman syndrome.
As this is an explorative design, no formal hypothesis is made. However, our sample size is based on a difference of 2.5% or more in cumulative incidence of serious infections when continuing IA, hypothesizing that patients who continue their IA in…
Based on the results of EMDR studies in older children aged 8-18 years and adults, it is hypothesized that EMDR will lead to reductions in post-traumatic stress symptoms, co-morbid emotional and behavioral problems. Additionally, we expect that EMDR…
To compare gastrointestinal digestion (gastric emptying and postprandial amino acids dynamics) between two dairy-based drinks containing casein and matched on macronutrient composition but differing in mineral composition.
There might be discrepancies in number and type of Cancer Predisposition Syndrome diagnoses between the genotype first and the phenotype first approach.
Critical illness, along with the lack of zeitgebers on the PICU environment, and iatrogenic influences like medication and procedures, results in disturbed circadian rhythms in critically ill children, which is important for their recovery.
In patients with recently diagnosed PMR, MTX 25mg/week compared to placebo will lead to a higher proportion of patients in glucocorticoid free remission
The present study aims to evaluate efficacy and feasibility of an online group intervention for parents of children with cancer that focuses on the specific issues that play a role in parents coping with a child with cancer. Hypothesis: Participants…
1) To investigate the effect of either the consumption of 1 or 3 small meals compared to no meal during the night shift on alertness levels, gastrointestinal complaints and glucose levels. 2) To investigate the effect of low glycaemic loaded meal(s…
The main objective of the study is to assess the change in first morning void urine albumin-to-creatinine ratio across the study period. The secondary objective is to assess changes from baseline in systolic blood pressure, body weight, eGFR and…
To determine which patients, individually classified for VTE ánd bleeding risk, will benefit from prolonged anticoagulant treatment without being unnecessarily exposed to its risks.
PCT-guided treatment regarding antibiotic use is non-inferior to usual care consisting of prednisolone and or antibiotics, in terms of treatment failure at day 30 for patients hospitalized because of an acute exacerbation of COPD (AECOPD).
The aim of this study is to investigate the effect of two distalisation techniques of a gastric bypass in revisional surgery with standardised limb lengths in total weight loss (TWL) and the need for treatment for protein calorie malnutrition (PCM…
The project proposed here aims to leverage recent advancements in fMRI methodology and lucid dreaming induction strategies to investigate brain networks and connectivity during REM sleep and its associated lucid vs. non-lucid dream experiences.
We aim to perform an in-depth investigation into the role of the mucosal immune response in the pathogenesis of rheumatoid arthritis. Our objectives are to study the presence of RA-specific autoantibodies and several other biomarkers (cytokines,…
This study aims to phenotype and endotype bronchiectasis during stable disease and exacerbations, to develop strategies for personalised medicine.3.1 Primary ObjectiveTo determine molecular endotypes of bronchiectasis which can guide response to…
The two main objectives are: A) identify patterns of psychofysiological stress in staff and clients prior to challenging behaviour, and B) explore possibilities of biofeedback on the psychofysiological stress level of staff, and whether biofeedback…