1584 results
•To determine the effect of hyperglycemic dysregulation on sleep characteristics (duration and quality), in patients with DM1 'What are the effects of controlled hyperglycemia on sleep characteristics (sleep duration and/or quality) in patients…
Primary objective: to assess the correlation and agreement between the new TB technique and the conventional SB online technique with constant expiratory flow.Secondary objective: to investigate the reproducibility of this new technique.
The effects of kidney transplantation on circadian rhythm. Focus on sleep and cardiometabolic risks.
Primary Objective: - What influence has kidney transplantation on (recovery of) melatonin production?Secondary Objective(s): - Is recovery of melatonin rhythm after kidney transplantation related to improvement of other circadian rhythms, e.g. body…
The aim of the study is to examine the effect of propranolol on intrusive memories of people suffering from a specific phobia (i.e. dental phobia). It is hypothesized that the administration of propranolol prior to dental treatment:1. would be…
Testing the hemostasis of oral surgery wounds with the HemCon dental dressing in patients on oral anticoagulation therapy
The main objective is to translate and adapt the Adolescent Cannabis Check-Up (ACCU) to the Dutch context and setting, and to evaluate its effects on the cannabis use of adolescents in the Netherlands. The Dutch version of the ACCU is called Wiet-…
The aim of the study is twofold:1) Examining cognitive and memory biases in depressed patients, patients in remission, and healthy controls. This will be investigated using an emotional Stroop task, working memory task and eye-tracking equipment.2)…
To optimize independent functioning and quality of life through:1. Systematic screening for increased risk of functional loss among community dwelling elderly (Phase 1);2. Providing a nurse-led, complex intervention to elderly people with an…
Please see pages 3-5 of the Protocol
In this study we aim to investigate the long-term results of the prepuberal orchidopexie for the acquired undescended testis. The volume and location of the testis are primary outcome parameters that display the result. This information will…
To quantify the amount of local anaesthetic in shed blood in the Bellovac ABT system and in the blood circulation of the patient. The primary objective is to detect the course of ropivacaine levels in the shed blood collected with the Bellovac ABT…
To assess the usefulness (sensitivity) of magnetic resonance imaging (MRI) in detecting TCP-induced changes in neurobiological markers induced by engine oil fumes.
1. To investigate whether we are able to initiate and measure the continence and defecation reflex in healthy human volunteers with our new method. 2. To compare the results of these measurements with those of existing techniques.3. To investigate…
The purpose of this study is to evaluate whether the Anchor Peg Glenoid provides adequate stability in the first en second year after surgery. Therefore, the migration pattern is determined after 3, 6. 12 and 24 months. The correlation with…
(voor meer details zie CMO-protocol paragraaf 2: Objectives) Primary Objective: The objective of this project is to further refine N-of-1 trial methodology, and explore whether Bayesian analysis of multiple N-of-1 trials can serve as a sufficient…
This will be a pilot study that aims to gain insight into the effect of Gaucher disease on bone metabolism. For this purpose we formulated the following research questions:What is the effect of inflammatory factors in the serum of patients with…
The aim of the present study is to use a more complete analysis of spinal motion (using a 3D multi-segment spine model) and to introduce challenging gait tasks which can optimally reveal the compensation strategies of the spine. Furthermore, static…
The aim of this study is to investigate whether the MTG and IFG serve dissociable roles in the storage and integration of lexical information in sentence comprehension. We will test this by applying rTMS to each of these areas on separate days as…
Subcutaneous stimulation as add on therapy to spinal cord stimulaion to treat low back pain in FBSS.
The aim of the randomized controlled study is to evaluate the effect of SubQ on low back pain in FBSS patients for whom SCS gives an inadequate back pain relief. We hypothesize that SubQ in addition to SCS in FBSS patients with leg and low back pain…
Four weeks after discharge what are the effects of telemonitoring with patients after cardiac surgery on: 1. Quality of life (SF-36)2. The number of readmissions within four weeks3. The number of relevant complications:atrial fibrillationrelapse…