164 results
The effect of mebeverine on abdominal pain intensity and frequency in children with irritable bowel syndrome or functional abdominal pain – not otherwise specified will be effective.
Analyze the protective effect of intranasal corticosteroids against exercise induced upper and lower airway obstruction
1) To investigate the efficacy of EEG-neurofeedback in reducing behavioral symptoms of ADHD.2) To investigate whether EEG-neurofeedback is able to improve neurocognitive functioning. 3) To investigate whether EEG-neurofeedback is able to improve…
Analyze the protective effect of levocetirizine (LEV), through the direct antagonism of airway H1 receptors and the inhibition of the release or production of other inflammatory mediators, against exercise induced airway obstruction.
Determine the influence of methylphenidate treatment on sleep-wake rhythm and endogenous melatonin rhythm.
The purpose of this study is to evaluate the safety and effectiveness of adalimumab for the treatment of moderate to severe Crohn*s disease in children between 6-17 years of age. In addition, information will be collected to select the most…
To characterize the multiple-dose pharmacokinetics of varenicline in adolescent maleand female smoking subjects
The objective of the study is to establish the effect of genestein in patients with MPS III on urinary and serum GAGs levels, hair morphology, GAG accumulation in skinbiopsy, cognitive functions and behavior (Piotrowska et al, 2008).MPS III is a…
Our aim is to find methods to effectively reduce the caries incidence during orthodontic treatment with fixed appliances. A secondary aim is to study the effect of fixed orthodontic appliances on the plaque ecology in relation to caries development.
The purpose of this study is to examine the efficacy and safety of 26 weeks treatment with inhaled mannitol in subjects with cystic fibrosis. Previous studies with inhaled mannitol have demonstrated improvements in lung function, mucociliary…
- To educate adolescents on clinical drug studies by involving them as project team members and participants in an intervention trial of negligible risk and minimal burden; - To investigate the CNS effects of caffeine on neurocognitive and…
Primary Objective:To evaluate the efficacy of OxabactTM to reduce urinary oxalate levels (molar oxalate to creatinine ratio) from Baseline to Week 24 in subjects with Primary Hyperoxaluria (PH).Secondary Objectives- To evaluate the safety of…
The objectives of this study are to establish whether methylphenidate PD effects can be measured using neurocognitive tasks, to describe the drug concentrations of methylphenidate in saliva, to describe the PK/PD relationship using the obtained…
To assess the efficacy of idebenone, compared to placebo, in improving or delaying the loss of respiratory function in patients with DMD
We hypothesize that nebulisation of ipratropiumbromide results in decreased production of sputum resulting in a better lung aeration (defined by an increase in EELV) and improved oxygenation (as defined by the PaO2/FiO2 ratio and the oxygenation…
Primary:The primary objective of this study is to evaluate the efficacy of LDX administered as a daily morning dose (30, 50, and 70mg/day) compared to placebo over the course of 7 weeks. This study will enrol children and adolescents (6-17 years of…
To show that treatment with SUBLIVAC® Grasses is clinically effective by means of reduction in allergic symptoms and/or use of allergic symptomatic medication in subjects suffering from IgE mediated allergic complaints triggered by grass pollen.
The goal of this study is to determine whether a short course of amoxicillin/clavulanic acid reduces the number of urinary tract infections in children that have been catheterized during a short period.
The aim of this study is determine the efficacy and safety of Metformin as a weight reducing drug in the euglykemic, obese paediatric population.
To evaluate the efficacy of inhaled rhDNase in addition to conventional treatment in children with an atelectasis during mechanical ventilation.