914 results
To evaluate the safety and efficacy of once daily application of omiganan topical gel compared to vehicle topical gel in subjects with papulopustular rosacea.
Given the significant number of patients with OIPN and the possible prophylactic properties of venlafaxine, this study is designed. This study will consist of a randomised placebo-controlled clinical trial to study the prophylactic effect of…
The principal aims of the study are to assess: 1. The effectiveness of a 5 day treatment course in arresting/ resolving episodic knee arthralgia/ flaring knee pain.2. The relative effectiveness of a low dose (1200 mg/day) of lipid formulated…
The primary objective is to determine the effects of dietary nitrate (beet root juice) on the microcirculatory profile in healthy adults. The secondary objectives are 1) to determine the effects of dietary nitrate on macrocirculatory parameters, 2)…
To evaluate the efficacy of HDM-SPIRE in the reduction of symptoms and the use of allergy rescue medication associated with HDM allergy in subjects with clinically relevant symptoms.
Primary objective is to examine the effect of tryptophan supplementation on the number of accepted unfair offers in the Ultimatum Game. Secondary objectives are to examine the effect of tryptophan supplementation on the response bias in a social…
This monocenter randomized controlled trial aims to compare postoperative outcomes of a laparoscopic valvuloplasty with a Toupet fundoplication in patients with GERD with a maximum hiatal hernia of 3cm. In addition, an economic evaluation of the new…
Objective: non-inferiority in fixation of the SL-PLUS MIA compared to the traditional SL-Plus stem and superiority of the SL-PLUS MIA in terms of bone and muscle preservation and thereby increased patient satisfaction and outcome as measured by PROM…
Primary:• To demonstrate the therapeutic equivalence of ONS-3010 (adalimumab biosimilar) compared toHumira® (adalimumab) in patients with plaque psoriasis Secondary:• To assess the safety, tolerability, and immunogenicity of ONS-3010 compared to…
To evaluate the efficacy of VX-661 in combination with ivacaftor through 24 weeks of treatment in subjects with cystic fibrosis (CF) who are homozygous for the F508del mutation on the CF transmembrane conductance regulator (CFTR) gene.
Primary Objective: To determine the effect of omega-3 PUFAs on exercise performance. Secondary Objective: To determine the effect of omega-3 polyunsaturated fatty acids supplementation on performance determining variables, such as VO2max, VO2 at the…
The primary objective of the study is to explore the effect of repetitive tDCS (left cathodal/right anodal) on mean daily cigarette consumption three months after tDCS by means of ecological momentary assessments (EMAs).To examine the course of…
Provide proof-of-concept for the hypothesis that guanfacine diminishes cognitive side-effects in ER+ BC patients treated with adjuvant hormonal therapy. Secondary, provide data for power calculations in later studies.
The aim of this study is to explore the effectiveness of repetitive bilateral tDCS (left cathodal/right anodal) over the DLPFC on relapse in cocaine addicts. Craving, temptations and cognitive control functioning will be assessed as predictors of…
To evaluate the safety and efficacy of once daily application of omiganan topical gel compared to vehicle topical gel in subjects with papulopustular rosacea
The objective of the study is to investigate the bioequivalence of 2 different proteins with regards to bioavailabillity in healthy elderly after one oral bolus intake.
To evaluate the impact of electroencephalographic NarcotrendTM Index (NI) monitoring on the speed of emergence and recovery from PPS for PGE.
to investigate the analgesic effect of high frequency 10 Hz rTMS on experimental pain measured through quantitative sensory testing (QST) in healthy subjects.
As meeting protein requirements seems to be very important in critically ill patients, the primary objective of the current study is to investigate protein intake with the new tube feed.
Primary:• To prove the superiority of a 12-week add-on treatment with 3.2 g/daygastro-resistant phosphatidylcholine granules (LT-02) in at least one of twodifferent dosing regimens versus LT-02 placebo for the induction ofremission in patients with…