378 results
This is a FIH study for M528101. We expect that the compound is safe and tolerable.
Succes-rate of discontinuation is higher with more gradual tapering of paroxetine or venlafaxine
We hypothesis that collagen supplementation augments the benefits of jumping exercise for bone metabolism.
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
The goal of this trial is to investigate whether (and at which dose or ratio) CBD has a modulating effect on the psychotropic effects of THC by comparing the effects of THC to the combination of THC with CBD in a range of ratios. Simultaneously,…
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
To reduce fatigue symptoms with the use of a bovine lactoferrin supplement in patients suffering from Long COVID.
We hyopthesize that in SCCH patients 3-monthly pamidronate decreases locally increased bone turnover (measured by Na18F-PET scans) and thereby decreases pain, and leads to improvement in shoulder girdle function, quality of life, physical and work…
There is no difference in information retention in patients when educated preoperatively by telephone or by video.
1. There will be a significant improvement in cognitive control, attention bias and memory bias performance after completion of the selected training module in the active vs. control training. 2. Rumination and depressive symptom severity will…
Infants’ growth when consuming hydrolysate-based formula is similar to growth when consuming a control formula with intact protein.
A positive effect on mood is expected after LSD (20 µg) compared to placebo. The effect of LSD on mood is expected to differ depending on time of drug administration (morning vs evening).
The purpose of this study is to investigate how safe the new compound KCP506 is and how well it is tolerated when it is administered to healthy volunteers. It will also be investigated how quickly and to what extent KCP506 is absorbed and eliminated…
We hypothesize that treatment with Sustained Release Calcium Butyrate (SRCaBu) will ameliorate: 1) the intestinal microbiome, intestinal barrier function and immune tolerance: 2) lower systemic inflammation of OA of the hand.
Riluzole treatment will reduce psychotic and cognitive symptoms
There are no differences in patients percieved outcome score (WOMAC) between a posterior cruciate retaining (PCR) total knee arthroplasty compared with a posterior stabilized (PS) total knee arthroplasty > 10 years postoperative.
Rationale: Loss of smell (anosmia) is common in COVID-19 infections. Most patients regain normal smell within 4 weeks, but in 6-8% the smell does not fully recovery. These persistent smell disorders greatly influence daily life. It is thought that…
Atypical scores on the IMP-SINDA at infant age is predictive for developmental disorders at the age of 4 or 5 years.
As the pain quality item “unpleasantness” delineates EB pain, we hypothesize the modulation of affective pain processing in the brain by way of intervention with Transvamix (a CBM comprising THC and CBD) - objectified by functional magnetic…
We hypothesize that the use of intrathecal morphine reduces postoperative pain and opioid consumption, which in turn will reduce the incidence of delirium.