97 results
Primary Objectives-To evaluate if mitochondrial dysfunction can be induced in healthy, middle aged subjects, through the use of simvastatin, and whether it can be reversed by oral ubiquinol supplementation. -To validate the techniques NIRS, PpIX-…
Primary objectiveTo evaluate the efficacy of low dose intravenously lidocaine in comparison with placebo in terms of pain relief after the first oxaliplatin administration measured by a numeric rating scale (NRS 0-10).Secondary objectives1.…
Evaluation of the histologically proven adenoma or carcinoma detection rate in patients undergoing a full colonoscopy with and without mucosal contrast enhancement, obtained with 200 mg of Methylene Blue MMX® tablets. The lack of mucosal contrast,…
Treatment strategy in early HCC aims at the local removal of the tumor and represents a potentially curative treatment option (resection, liver transplantation, PEI, RFA, BT). Patients in intermediate and advanced stage of HCC receive treatment with…
EFFICACY OBJECTIVESThe primary efficacy objective of this study is to evaluate the efficacy of intravitreal injections of 10 mg lampalizumab administered Q4W or Q6W in CFI profile biomarker positive and CFI profile biomarker-negative patients…
To determine whether the use of epinephrine saline irrigation in therapeutic shoulder arthroscopy with need for subacromial procedures should significantly increase clarity of the view.
The objectives of this trial are:- To compare experienced pain during GIS using ExEmgel versus Endosgel (continuous measure pain and subjective reported VAS score)- To compare the image quality, including the occurrence of air bubbles during both…
to assess whether a single-dose of levodopa improves cognitive symptoms and balances goal-directed and habitual behavior.
Compare sensitivity and specificity of both rules as well as compare the accuracy between observer groups for these rules. Also the interobserver agreement is assessed to test whether the rules are reproducible.
1. To determine clinical symptoms of Dientamoeba fragilis infection. 2. To evaluate the efficacy and safety of clioquinol versus metronidazol in the treatment of Dientamoeba fragilis in children.3. To evaluate the duration of positive PCR…
Primary objective(s):To evaluate the effect of early haloperidol prophylaxis on the incidence, severity and duration of in-hospital delirium in at-risk patients aged 70 years and over who are acutely admitted to the hospital through the ED, for…
We propose to conduct a study in patients with mild to moderate AD where a cholinergic challenge is given in a placebo-controlled, cross-over fashion, prior to onset of treatment with a CEI. Patients will be followed over a period of 6 months to…
Objective of the study is to asses quality of fracture reduction and patient-relevant outcomes with the intra-operative use of the 3D-RX-system as compared to the conventional 2D-fluoroscopy in patients with traumatic intra-articular fractures of…
The main objective is to study pregnancy rates after using metabolomic profiling added to the selection of viable embryos by morphology, compared to using only morphology.
The main objective of this study is to assess the efficiency of oxytocin compared to placebo as an addition to the exposure sessions in the treatment of PTSD. We hypothesize that adding oxytocin to exposure in TF-CBT produces acute changes in…
Change from baseline in regional cerebral blood flow in response to various visual stimuli ascertained by Positron Emission Tomography scan after 8 weeks of flibanserin 100 mg treatment.
Main objectiveLorazepam is frequently used as an anaesthesiological premedication before surgery in order to reduce patients resistance. Does lorazepam also improve the quality of recovery in patients scheduled for day-case-surgery?Secondary…
To assess whether testing for fibronectin is a cost-effective strategy that prevents unnecessary treatment in women with threatened preterm labour.
The primary objective in this study is to evaluate effectiveness of optimized high cervical epidural neurostimulation against placebo-stimulation in patients with intractable cervicogenic headache in a neurostimulation trial.
To assess whether cholangiography using the Kumar clamp is faster and easier than using the Olsen catheter.