3292 results
Primary objective: Can application of diagnostic ultrasound and microbubbles enhance epicardial coronary recanalization with a lower and safer dose of a thrombolytic agent such as alteplase 50mg when combined with normal care consisting of prasugrel…
To investigate whether sustained trough levels of IFX can be achieved using IFX trough level measurements and adjustment of dosing based upon these levels by means of two different standardized algorithms in comparison with *standard of care* IFX…
The Claret device (Claret Inc.) is an Embolic Protection Device (EPD) consisting of two nitinol baskets to be introduced through the right radial artery. One basket is positioned in the brachiocephalic trunk, the other in the left common carotid…
The aim of the study is to evaluate the effectiveness of an activity stimulation program on performance of mobility and lifestyle in children with cerebral palsy, in comparison with regular paediatric physiotherapy.
The objective of this study is threefold:1) compare the effectiveness and cost-effectiveness of brief CT added to maintenance AD versus maintenance AD alone versus guided tapering or discontinuation of AD with brief CT.2) examine whether the…
To determine whether rehabilitation treatment strategies effectively reduce fatigue and improve participation in MS patients with fatigue, and how they exert their effects.Research questionsQ1) Does AT result in reduced fatigue and improved…
The objective of this project is to assess whether CBT-E is more optimal in terms of (cost-)effectiveness than TAU in thetreatment of outpatients with an ED. The results of this study will provide evidence whether or not CBT-E should be delivered…
This study will form the basis for future studies that are planned to investigate chemosensory disturbances in elderly and testicular cancer patients who are undergoing cisplatin based chemotherapy within the University Medical Center Groningen.…
In this study, we aim to improve recognition of delirium in a palliative care population with advancedcancer and we aim to provide evidence for optimal treatment of delirium through adequate dosing ofpreferred neuroleptic.Primary objectives:1) To…
Primary research questions To investigate whether the outcome after the randomized implantation of the Resolute Integrity® versus Promus Element® drug-eluting stent are similar, as assessed in a non-inferiority setting by comparing target-vessel…
Our study tries to identify the ideal sclerosant dosage for the ClariVein® system in order to occlude the GSV permanently. By choosing the lowest dose with the same anatomical success rate, we achieve a safe treatment which also gives us the…
In the proposed study we aim to investigate determinants of frailty and the effectiveness of a of a structured multi-dimensional intervention program called **KWIEK** on frailty, self-care/functional abilities and quality of life, in different…
Aim of the study is to compare the efficacy and safety of the use of a low vacuum constant drainage system (Palin®) with a high vacuum closed suction drainage system (Medinorm S-400®) after chest wall masculinization in female-to-male transgenders.
The main objective of our study is to evaluate in a randomized clinical trial the long-term clinical effectiveness of brief C-PCT in high risk recurrently depressed patients (responding to A-CT), compared with care-as-usual (monitoring). High risk…
Primary objective: To determine the reduction of number of patients who receive blood transfusion perioperatively in the group pre-treated with erythropoietin and iron supplement compared to the control patients.
To compare the digestibility, bioavailability and subsequent muscle protein synthetic response to casein, with casein protein provided in an isolated manner versus casein in a milk matrix, in healthy elderly subjects
Primary Objective: The aim of this study is to determine a cut-off score at the PQ-16 with the CAARMS for better detection of adolescents 12-18 years at risk. Secondary Objective(s): To study the course of UHR in adolescents 12-18 years over a one…
Evaluation of the cosmetic result after 12 months of transcutaneous sutures versus intracutaneous sutures in the craniofacial area.
To investigate the effects of the different combinations of propofol and remifentanil on the isobole of TOL90 and to compare hemodynamics, cerebral and tissue oxygenation for each equipotent combination. To describe the combination of propofol and…
To assess if preoxygenation with 100% O2 or preoxygenation with 100% O2 and PEEP are different with respect to the development of atelectasis as determined by lung computed tomography.