26721 results
Based on literature we assume a 20% day 30 mortality of patients admitted to the hospital ward with COVID-19. We aim to lower this day 30 mortality to 10%.
The procoagulant state seen in patients with hiv can be a result of the immune activation due to the hiv infection itself or combination antiretroviral therapy (cART). In case the acquired thrombophilia is a result of immune activation, the…
ICT guided disease management combined with telemonitoring leads to a reduction of death and readmission for heart failure, and improves the quality of life.
The goal of EEG4STROKE is to test a device that enables paramedics to accurately diagnose patients with suspected stroke on site (in the ambulance or living room of the patient). EEG4STROKE will integrate hardware and software to triage stroke…
Primary objective: To test whether mucosal oxygen saturation has added value to endoscopy and histological examination. Secondary objectives: 1. To test whether detection of hypoxia dependent molecular changes in the mucosa can be used to improve…
HIV-infection and antiretroviral therapy use may lead to a diminished neurological and neurocognitive performance in HIV-infected children.
Early provision of AFOs (± 2 wks after stroke) is expected to positively affect walking impairments, mobility and activities of daily living after acute stroke compared to providing AFOs later on in the rehabilitation process (± 10 wks after stroke…
1) In what proportion of severe hypoxic COVID-19 patients on HFNC is invasive mechanical ventilation necessary? 2) In what proportion of severe hypoxic COVID-19 patients with an DNI code on HFNC results in progressive respiratory failure or death?
Since several years, anti-VEGF agents have become available for the treatment of neovascular age-related macular degeneration (AMD) and have substantially improved visual prognosis in patients suffering from this condition. The anti-VEGF agent used…
Diaphragm thickness is constant throughout the zone of apposition in craniotomy-caudal direction
The rationale for this study is to assess the visibility and positional accuracy of the laser marks. Combined with VLE imagery, the targeting enabled by the laser marking system could have the potential to increase the diagnostic accuracy of current…
The hypothesis of this trial is that reusable catheters are as safe and efficient as single use catheters and will be cost-effective.
The primary objective of this study is to evaluate the effect of surgical correction of pes equinovarus deformity compared to conservative treatment on personalized goal attainment. In addition, we will evaluate the effect of surgical correction of…
The hypothesis is that a 5-week perturbation-based training program using the Radboud Falls Simulator (RFS) will improve the mechanical efficiency of stepping to recover balance in community-dwelling persons in the chronic phase after stroke.
Emerging techniques measuring oxidative APAP metabolites and microRNA-122 (miR-122) could make it possible to detect paracetamol induced liver injury earlier and more precisely than currently used paracetamol plasma concentrations and clinical…
We hypothesize that the MACE and mortality rates will be very low, due to mild or absent coronary disease on the CCTA and the short follow-up duration.
Does lipid accumulation in skeletal muscle and the heart effect mitochondrial function in relation to insulin resistance?
Treatment with Infliximab will reduce loss of visual acuity by 8 letters or better on the ETDRS chart.
We hypothesize that there is no difference in the number of patients experiencing partial flap loss at six months post operative.
The intention to change behavior is related to changes in multiple physiological variables. Thermal comfort and thermal sensation are related to these physiological parameters. Furthermore, the intention of behavior is related to changes in thermal…