267 results
Smell and taste function change during chemotherapy consequently affecting 1) dietary intake 2) eating behavior 3) anthropometry 4) quality of life
The objectives are firstly that Love is... promotes the healthy sexual development by increasing knowledge and positive attitudes towards sexuality. Secondly, characteristics of adolescents who do not improve from the general prevention program are…
This multicentre randomised controlled trial aims to investigate whether PoCUS can be used as an adjunct to improve first attempt success rate in closed reductions of displaced distal radial fractures in adults in the ED.
The standard-of-care sentinel lymph node (SLN) procedure in paediatric cancer patients consists of a preoperative intradermal injection with 99mTechnetium-nanocolloid as radiotracer in combination with an intraoperative injection of blue dye for…
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
The aim of the Continuous versus Intermittent Nutrition in Pediatric Intensive Care randomized controlled trial (RCT) is to investigate a strategy of intermittent nutrition with a focus on an overnight feeding interruption period versus 24-hour…
To visualize and quantify areas of dysfunctional flow in the TCPC and within the single ventricle in patients after a Fontan procedure and try to determine a relationship between these quantitative energetic parameters and adverse outcome.
To examine the effect of a physical activity intervention on executive functioning, mental health and academic achievement in healthy adolescents. The secundaire objective is to examine the effect of a physical activity intervention on physical…
We aim to prevent or reverse developmental regression in patients with Kleefstra syndrome. We hypothesise that the regression we observed is the result of a psychotic disorder, which isnot properly recognised by clinicians and often not treated…
- What is the echogenicity (quantitative described as z-scores, based on own laboratory values and qualitatively described as Heckmatt gradations) of orofacial muscles (digastrics muscle, geniohyoid muscle, masseter muscle, temporal muscle) in…
The aim is to study the feasibility of a brief, intensive, outpatient group treatment (ERP) for youths with chronic tic disorders/Tourette Syndrome (TS), to improve treatment outcome, daily functioning/quality of life and treatment satisfaction.…
1) To investigate the effectiveness of Multi-family therapy (MFT) versus individual oriented treatment as usual (TAU) on end-of-treatment family functioning of veteran families, as reported by the veteran. TAU consists of supportive counselling or…
To investigate whether age-related differences in grammar acquisition primarily reflect maturational changes in neural plasticity and pathways that support learning and consolidating of new linguistic knowledge and skills.
Primary Objectives:-To evaluate if the treatment of Low Risk HB can be reduced (Group B1)-To compare different induction treatment regimens for Intermediate risk HB (Group C)-To compare different post induction treatment regimens for High Risk HB (…
The aim of the study is to investigate the effect of an intensive high frequent parental coaching intervention on communicative abilities in patients with AS. Patients with AS who receive standard care, will serve as controls. Parents/caretakers in…
Primary Objectives* To evaluate the efficacy of golimumab in inducing clinical remission as assessed by the Mayo score,in pediatric participants with moderately to severely active ulcerative colitis (UC).* To evaluate the safety profile of golimumab…
• Primary Objective: To evaluate the effect of azacitidine treatment in AML subjects at molecular relapse after CR1 with regard to molecular response prior to further treatment (reinduction / HSCT)• Secondary Objectives:o To assess safety of…
Primary Objective• To assess the safety and tolerability of 3 single ascending dose (SAD) levels and 3 MAD levels of DYN101.Secondary Objectives• To assess the PK of SAD and MAD of DYN101.• To explore target engagement in muscle of DYN101.…
To investigate neural response patterns to visually and orally presented palatable (high vs low caloric) and unpalatable (high vs low caloric) foods in AN patients and matched healthy controls (HC). This will be investigated through 1 study with 2…