1695 results
To monitor the systemic effects of radiotherapy (RT) alone or in combination with concurrent chemotherapy (CRT) (Cisplatin) on the immune response and T-cells over time in patients with HPV+ head and neck squamous cell carcinoma (HNSCC).
To test the suitability of OCT for in vivo imaging of the vascularisation and surrounding tissue of burn wounds and scars.
Aim1. To investigate the long-term effects of early detection and intervention of hearing loss on the development of children with congenital bilateral hearing impairment. 2. To define factors in early childhood that are able to predict…
The purpose of this study is to test whether perceptual expectations modulate V1 activity consistent with *hypo-priors* in autistic individuals.
The main objective of this study is to investigate the predictability of persisting post-surgical pain (PPSP) after TKA using electrical quantitative sensory testing (eQST) and nociceptive perception thresholds (NPT) in combination with a pre-…
The purpose of the study is to evaluate the usability of PatientCoach by patients with asthma and/ or COPD,hypertension and/or Diabetes Mellitus.
To determine the feasibility of a home based rehabilitation program delivered by means of a tablet-pc for patients after THA To get a first impression of the clinical effectiveness of the rehabilitation program
The purpose of this study is: 1. To investigate the differential effectiveness of group and individual parent training in PRT on opportunities created by parents and social initiations of children with Autism Spectrum Disorder (ASD). 2. To…
To elucidate the molecular mechanisms underlying renal disease that lead to chronic kidney disease. To validate pathogenic variations in functional in vivo models.
The objective of this study is to investigate whether the differences in DNA methylation between individuals who were exposed in utero to the Dutch Hungerwinter (F1) and their non-exposed, same-sex siblings (F1) - as identified in epigenome-wide…
There are 3 possible explanations for the differences. First: handposition; Soteropoulos et al. (2011) used a pronated handposition (hand palm flat on the table surface) during index finger abduction while during our experiment the handposition was…
Determine the repeatability, inter and intra-observer variability of the *Scolibed*. Determine the variation in stiffness for healthy individuals and for scoliotic patients. Compare the results of healthy individuals and scoliotic patients.
• To assess the prevalence of short stature, in combination with an aberrant IGF-1 in combination with IGF-BP3 in the entire cohort of childhood cancer survivors and the therapy related risk factors.• To assess the distribution of IGF-1 and IGF-BP3…
The aim of this study is to assess the prognostic value of sarcopenia and geriatric markers for survival and treatment tolerability and fluctuation of this value between several oncologic conditions. Secondly, we focus on the value of repeated CGA…
the aim of this study is to compare the impact of an early-CR within 48 hrs. after PPCI to a late complete revascularization >2 weeks after PPCI on LV remodelling in patients with STEMI and multi-vessel disease.
To demonstrate efficacy of adjuvant combination chemotherapy in a randomized phase III trial comparing to no further treatment in the medium and high-risk node negative stage I and stage II patients.
The primary objective of this study will be to evaluate the cardiac adaptation due to hemodynamic changes in monochorionic twin pregnancies complicated by TTTS and sIUGR, by evaluating the size and the growth pattern of the pulmonary artery and the…
The primary study objective is to assess the proportion of patients who remain within the IGF-I age adjusted normal limits with pasireotide LAR (60 mg) monotherapy, after 24 weeks of treatment.Secondary study objectives are assessment of the…
(i) identification and cellular characteristics of red blood cells from patients with altered ion homeostasis and delivery of novel and easy-to-use diagnostics for rare anemia*s, for patients with: a) a known primary defect in the ion channels of…
The study will collect data related to symptoms of recurrent biliary stent obstruction requiring reintervention, adverse events, and a variety of important secondary endpoints including technical success and time to symptomatic recurrent biliary…