1605 results
Prelingually deafened cochlear implant users mostly do not achieve a high level of speech understanding with their cochlear implant (CI). We hypothesize that the information these patients are getting from their CI is often too complex for them to…
The intention to change behavior is related to changes in multiple physiological variables. Thermal comfort and thermal sensation are related to these physiological parameters. Furthermore, the intention of behavior is related to changes in thermal…
The purpose of this study is: 1. To identify clinical and biological predictors for the development of IRIS in HIV infected patients and; 2. To obtain insight into the pathogenesis of this syndrome; 3. To describe the epidemiological pattern of IRIS…
We hypothesize that more participants in the experimental condition, who are offered the computer-tailored feedback program, will quit smoking and that these participants will become more physically active compared to the participants in the control…
We hypothesize that the vascularity of the fibroid is associated with: 1. Growth potential of the fibroid; 2. The fibroid size reduction after GnRHa treatment.
Exploring QOL, hope, treatment motivition, coping en locus of control of patients considering early clinical cancer trial participation.
Amendment (5-apr-2013): Dosing-time of sunitinib may alter the pharmacokinetics
TEE has proven to be an invaluable tool in evaluation and guiding treatment in both adult and paediatric patients in the operating room and in the ICU. In the ICU the development of smaller TEE probes has led to the trans-nasal introduction of these…
1. Cancer survivors experience more meaning in life after the intervention; 2. Psychological wellbeing in cancer survivors improves after the intervention.
High-dose, weekly erlotinib is a therapeutic option for EGFR-mutated NSCLC patients with leptomeningeal metastases while on EGFR-TKI therapy. In one of the patients treated with this dose schedule not only the leptomeningeal metastases showed…
Yellow fever specific T cells are present in 70% of patients using immunosuppressive medication versus 99% of healthy volunteers.
It is expected that using the DEM-DISC will decrease the number of unmet needs and increase the number of met needs in people with dementia and their informal caregivers. Informal caregivers using DEM-DISC are expected to feel less burdened and will…
The aim of this study is to test, by means of a randomized controlled trial, the hypothesis that application of PAS therapy with low-frequency acoustic vibrations to demented patients in nursing homes will lead to a significant decrease of nocturnal…
Combination therapy with telaprevir/ ribavirin is as effective as the current standard of care with peginterferon-alfa/ ribavirin for the treatment of acute Hepatitis C in HIV-infected individuals.
We hypothesize that RPCA is as effective in reducing pain relief scores as EA, with lower costs and easier achievement of 24 hours availability of pain relief for low risk women in labor.
1. That adherence to the WHO recommendations (2003) for early child feeding among low-income Quetzaltenango mothers, specifically exclusive breastfeeding up to 6 months, is associated with higher growth attainment and greater disease resistance; 2.…
Intra-operative evaluation of efficacy and safety of a new lead for steering Deep Brain Stimulation.
Primary Hypothesis: 1. Sapiens lead is able to provide stimulation to the brain safely and elicit equivalent effects as commercial DBS systems. Secondary Hypotheses: 1. Steering can modulate the thresholds of stimulation-induced effects; 2. The…
For patients with a diffuse large B cell lymphoma (DLBCL) the efficacy of the anti-CD20 monoclonal antibody rituximab combined with salvage chemotherapy in the second-line setting has decreased due to more effective first-line treatment with…
There will be a relation between the level lidocaine in newborn, the level in mother and drug-delivery interval.
The primary objective of this study is to evaluate the web-based intervention 'Leven met Pijn' in comparison to a minimal intervention condition and a waiting list control condition in terms of a decrease in pain interference in daily life…