4 results
Primary: To evaluate the efficacy of retigabine as adjunctive therapy to each of the following specified monotherapy AED treatments: carbamazepine/ oxcarbazepine, lamotrigine, levetiracetam or valproic acid in subjects with partial-onset seizures (…
Primary: Long-term safety and tolerability.Secondary: Long-term efficacy.
- The primary objective is to determine the dose limiting toxicity and the maximum tolerated dose and recommended dose of the combination of temsirolimus weekly and nelfinavir orally BID to patients with advanced solid tumors.- Secondary objective…
Primary ObjectiveThe primary objective is to assess safety and tolerability, describe the dose limiting toxicities (DLTs), and determine the maximum tolerated dose (MTD) or the maximum administered dose (MAD; in the absence of exceeding the MTD) for…