8 results
To determine the relation between tumor tissue phosphoproteomic profiles and progression-free survival (PFS) in patients with advanced RCC
To test the impact of the addition of axitinib to standard chemotherapy treatment on histology samples
To investigate efficacy of neoadjuvant axitinib and avelumab in patients with localized renal cell carcinoma with moderate to high risk of recurrence .
To establish the accuracy of the Medtrum TouchCare Nano 14 CGM system compared to thecurrent gold standards i.e. established central laboratory technique (the StatStrip Xpress®monitoring system (Nova Biomedical, Waltham, WA), the accuracy of a…
To analyse the safety of oestradiol in the setting of endocrine treatment for locally extended prostate cancer adjuvant to radiotherapy.
Sub-study APhase 1b:To assess the DLT rate and estimate the MTD of sasanlimab in combination with encorafenib and binimetinib to determine the RP2D for the combination. Phase 2:To assess the durable ORR of sasanlimab in combination with encorafenib…
Primary ObjectiveTo demonstrate that avelumab in combination with axitinib is superior to sunitinib monotherapy in prolonging PFS or OS in the first-line treatment of PD-L1 positive patients with aRCC.Secondary Objectives* To demonstrate that…
To establish the performance of the TouchCare Nano 14 CGM system among persons with DM.