4 results
To perform a percutaneous renal sympathetic denervation in a cohort of 20 patients with therapy resistant CPVT and LQTS patients and to objectify and evaluate the benefit of this novel treatment for this group of patients.
Primary: Safety and tolerability.Secondary: Clinical and endoscopic remission, symptomatic clinical remission, clinical response, mucosal healing, health related QoL, CRP, faecal calprotectin, pharmacokinetics.
Aim of the study is to study a new therapeutic option for the treatment of hypertension
Part 1: Dose-Escalation Stage (not in The Netherlands)Primary objective:* Safety and tolerability of HBM4003Secondary objectives:* Preliminary anti-tumor activities of HBM4003 in advanced solid tumors* Pharmacokinetics (PK) of HBM4003Other…