300 results
In this study we want to objectively measure the effect of Pirfenidone on cough in patients with IPF.
Objective: The aim of this study is to assess the validity of the 4MGS and 5STS to determine the functional exercise performance of PF patients.
The objective of this study is to demonstrate the influence of pectus excavatum on the anaerobic threshold during exercise. This could be an objective measurement of exercise intolerance. An objective measurement of exercise intolerance can later…
Investigate the phenotype, function and regulation of TRM in healthy human lung tissue, lung tumors and peripheral blood to improve the understanding of respiratory diseases and adoptive T-cell therapy for lung cancer.
Primary objectives:1.1 To investigate the differences between patients* and resident loved ones' perceptions of patients* health status and problematic ADLs.1.2 To study prospectively the effects of an acute COPD exacerbation on resident loved…
Objective: The main objective is to establish the strength of the relationship between improvements in dyspnea and health related Quality of Life (HR-QoL) with the decrease in hyperinflation during the resolution of a COPD exacerbation in the…
1. Feasibility and reproducibility of transcutaneous (tc) dEMG on premature neonates. - Are the signal quality (heart rate and respiratory rate), bradycardias and apneas similar to the current impedance monitoring2. Can we differentiate between…
Question: Is it an added value for the patient if there will be a default capsaicin provocation test to diagnose chronic cough?It will be investigated or with the aid of the capsaicin provocation test the diagnosis sensory hyperreactivity (SHR) can…
Primary objective:The primary objective is to answer the question: How do COPD patients experience intensive care unit admission because of exacerbation and what is the impact on their quality of life. This study aims to understand the perspective…
The primary objective of this study will be to evaluate the cardiac adaptation due to hemodynamic changes in monochorionic twin pregnancies complicated by TTTS and sIUGR, by evaluating the size and the growth pattern of the pulmonary artery and the…
This study will investigate the feasibility of a hypoxic challaenge test (60 minutes duration). During this test the inspired air will have a oxygen content of 15%. This is a comparable value as is used during a commercial airline flight (ca 2500…
Is pulmonary function testing using the Whistler device a feasible method in adults with an intellectual disability? Is pulmonary function testing using the Whistler device a reliable method in adults with an intellectual disability? Does the…
Main objective: To investigate Differences in sustainability of inhalation technique of Diskus® and Autohaler® in the home situation. This will be measured with the inhalation checklist for the Diskus® and Autohaler®. Secondary objectives: * To…
The main objective of this study is to assess more thoroughly the differences in gait patterns between COPD patients and healthy controls. Other objectives are to assess differences in gait patterns between GOLD stages and two age groups in healthy…
To study remodeling patterns of the left and right ventricle in patients with pulmonary arterial hypertension who underwent lung transplantation, using cardiac magnetic resonance imaging.
To investigate the direct effect of caffeine on the respiratory effort of the preterm infant at birth.
The purpose of this study is to compare the Metronome-Paced Hyperventilationtest (MPH) with cardiopulmonary exercise testing (CPET) in patients with COPD for detecting dynamic hyperinflation, thereby establishing the diagnostic accuracy for dynamic…
Main question: What is the lung function of late preterm births compared with children born at term at age 12? Sub-questions: - Which respiratory symptoms in late preterm infants at age 12?
Demonstrate the safety and efficacy of ventilation with Ventrain® during 5 minutes. Safety is demonstrated if the peak pressure during insufflation does not exceed 25 cm H2O and PEEP (Positive End Expiratory Pressure) is not smaller than -5 cm H2O…
Objective: to obtain lung function parameters in infants born preterm at the age of 6 months and to evaluate risk factors for impaired lung function