233 results
The purpose of this study was to determine the incidence and severity of co-infection in children hospitalised for bronchiolitis, when cohorting of RSV-infected patients is omitted. . Furthermore we want to elucidate general epidemiological data on…
This study is aimed to compare the changes of FRC after performance of three different placements of external stripes during recruitment maneuver
General objective:• Determine the prognostic value of T50 for treatment outcome of CCRT for NSCLC.Secondary objectives:• S1: Confirm the image quality of extremely low dose FDG PET/CT scans.• S1: Test the complex study logistic with all involved…
Primary objective- To define the optimal pressure support level for homogeneous lung ventilation during PSV, based on EIT measurements, in patients with and without lung disorders.Secondary objectives- Improved oxygenation compared to baseline-…
To study the effect of early tumour development on brown adipose tissue activity
Primary Objective: To determine the prevalence of endo- and extranasal deformities, problems with nasal functioning and satisfaction with nasal appearance in patients with TCS.Secondary Objective: To adjust and improve the treatment of patients with…
Primary objectiveTo detect the difference in mean arterial blood pressure between conventional APRV settings and APRV settings based on EIT measurements, in patients with ARDS.Secondary objectivesImproved dorsal ventilation distribution on EIT…
Our primary aim is to assess the (cost-)effects of the ACCESS system in the support of exacerbation self-management of patients with COPD.
To identify biomarkers associated with OSA in bariatric surgery patients prior to surgery; to investigate the effect of bariatric surgery on these with OSA associated biomarkers; to identify biomarkers that predict amelioration of OSA after…
Is pulmonary function testing using the Whistler device a feasible method in adults with an intellectual disability? Is pulmonary function testing using the Whistler device a reliable method in adults with an intellectual disability? Does the…
To optimize ventilator support in critically ill patients admitted to the intensive care unit by monitoring electromyography of the respiratory muscles.
Compare the performance of the Philips Respironics Sleep Therapy Auto System to a fixed CPAP device for the treatment of OSA and validate its event detection capabilities.
Lower tidal volumes in order to reduce VILI and days on the ventilator which will reduce the number of days on the ICU
Primary Objectives: 1. Is it feasible to visualize active inflammation in patients with pulmonary sarcoidosis by using Diffusion Weighted Imaging when compared to 18F-FDG PET?Secondary Objectives: 1. Is it feasible to visualize lymph node…
Primary Objective: 1. Will an exposure to oxygen with a PO2 = 190 kPa lead to changes primarily in DLno compared to DLco?Secondary Objectives: 1. After an exposure to oxygen with a PO2 = 190 kPa for one hour, are the changes primarily located in the…
We hypothesize that ER stress contributes to epithelial dysfunction in Z-AATD, resulting in enhanced inflammation. In addition, we hypothesize that the airways of Z-AATD patients are particularly prone to bacterial infection and colonization through…
PRIMARY OBJECTIVE1. To assess the effect of screening with AFB and subsequent treatment of endobronchial lesions in addition to screening with CT scan on cancer free survival of COPD patients previously treated for early stage NSCLC. SECONDARY…
The primary objective is to determine the efficacy (as measured by pulmonaryfunction) and safety of CNTO 888 in subjects with IPF. The major secondary objectives are to assess theeffect of CNTO 888 on measures of disease progression, to assess the…
To study the effect of reducing the pulmonary circulation to normal levels on the pulmonary leak index in patients suffering from severe ARDS.
First Objective: Is the percentage of subjects that dynamic hyperinflate during activities of daily living larger in patients with mild COPD than in healthy controls?Second Objective(s): Will dynamic hyperinflation induced by activities of daily…