25 results
To investigate the hypothesis that temporising treatment of women with early-onset, severe preeclampsia improves infant outcome and may reduce direct treatment costs in comparison to short-term planned delivery, while persistent maternal morbidity…
To assess in women with a request for pain relief during labour the cost-effectiveness of remifentanil patient controlled analgesia (RPCA) as first choice compared to EA.
Primary objective: To evaluate the efficiency of the daycare treatment of pregnant women with a psychiatric disorder.Secondary objective:Differs groupwise daycare treatment in efficiency towards standard individual outpatient care, in terms of:a.…
Primary Objective: To determine the accumulation of AGEs in the skin and serum of pregnant women with DM1, DM2 or GDM, in comparison to healthy pregnant women and non-pregnant women with DM1 or DM2 and to determine the accumulation of AGEs in the…
What is the most reliable way, defined as the lowest percentage rate of urines which are contaminated, to collect urine in pregnant women to asses bacteriuria? Comparison of three different methods of collection: midstream morning urine, midstream…
The main goal of this study is to examine the clinical applicability of the Monica AN24*, for the use of this device in the LUMC for prolonged CTG-registrations in high risk pregnancies and particularly in monitoring fetal cardiac arrhythmias. The…
To evaluate whether a higher SAF level is related to a higher incidence of macrosomiaTo evaluate if a higher SAF level is related to a higher incidence of other maternal, fetal or neonatal complications To evaluate is SAF level is related to a…
To collect maternal blood during the 2nd half of pregnany, in combination with clinical data and data on pregnancy outcome.
To investigate whether SAF is elevated in GDM versus non-diabetic pregnancy To investigate whther SAF levels change during the course of normal and GDM pregnancy To investigate if SAF is related to other parameters of hyperglycemia (HbA1c, self…
To assess the effects of a screening policy for Q fever in pregnant women from areas with large numbers of Q fever cases on the pregnancy outcome and cost-effectiveness from a societal and health care perspective.
To compare which treatment (indwelling catheter versus intermittend catheterisation) has the best clinical effect in women with symptomatic PUR.
The main objective of this study is to analyze women's decision making processes regarding an unintended pregnancy in order to improve the counseling (in abortion and reproductive health clinics) for these women.
To evaluate the predictive value of microcirculatory perfusion for the incidence of Extracorporeal Membrane Oxygenation (ECMO) dependency and consequently survival. To evaluate the effects of vasopressor drugs and iNO on microcirculatory perfusion.
To assess the effects of Cognitive Behavioral Therapy (CBT) in pregnant women with symptoms of anxiety or depression on the child*s behavioral/emotional problems. In addition, we aim to study its effects on the child*s development, maternal mental…
To compare the effectiveness of the tocolytic agents Nifedipine (a calcium channel blocking agent) versus Atosiban (an oxytocin receptor antagonist) in the improvement of neonatal outcome in women with threatened preterm labour (25-34 weeks…
To test The Selection Failure hypothesis by assessing A) the degree of embryo invasiveness and decidual acceptance (the quality of decidualization, endometrium-embryo communication and endometrial stromal cell (ESC) migration) and B) the angiogeneic…
Hypothesis.In women with preeclampsia endovascular remodeling and invasion of the spiral arteries is less prominent which will result in overwhelming placental oxidative stress and pregnancy failure. Abnormal function of trophoblast and stroma cells…
The primary objective of the PRIDE Study is to identify factors to which a woman is exposed during her pregnancy that have an influence on the health status of the mother and/or her (unborn) child. In addition, the evaluation of preconception,…
To determine whether fFN kan detect preterm delivery in monochorionic twins treated for TTTS.
At the Centre for Contraception, Sexuality and Abortion Leiden, abortion procedures are performed under deep sedation using Propofol. Patient*s monitoring is performed by nurses qualified in patient sedation management, using pulse oximetry and…