1098 results
Primary Objective:The overall aim of the study is to examine whether the early-childhood adversities experienced by the adoptees will be transmitted to the next generation or whether the cycle of early negative experiences has been broken.Secondary…
The primary objective of this study is to gain more knowledge about the mean and the distribution of mitochondrial oxygen tension (mitoPO2), the mitochondrial oxygen consumption (mitoVO2) and the affinity for oxygen of mitochondrial respiratory…
Knowledge about the physiological metabolism of SCFAs and the interorgan exchange of SCFAs across different abdominal organs in humans is lacking to some extent.To this end, the following objective will be addressed in the current study: -Determine…
The main objective is to evaluate the effectiveness of the intervention (Lifestyle Triple P).
At the stroke unit, exposure to the *Dynamic Adaptive Healing Light System* (DAHLS) following a predefined daily rhythm with low, medium or high intensities dependent of the medical status of the ischemic stroke patient is expected to improve the…
Objective 1: to examine the relation in wall thickness and diameter across arteries that are prone (i.e. carotid, femoral, superficial femoral and popliteal) and resistant (i.e. brachial and radial) against atherosclerosis in healthy volunteers and…
We have set prior to the design and implementation of this research a primary and a secondary goal.Primary goal:Testing the validity of the computer model of the coagulation cascade and the related PK / PD model of VKA and heparin for use in…
To enhance the (functional) communicative skills of children/adolescents with severe communicative problems with the use of specialized AAC aids in order to optimize their participation at home, in school and other social contexts.
The gaol of the present study is to determine the role of platelet derived TFPI on coagulation in healthy male subjects (n=10) and in healthy female subjects either using ( n=10) or not using oral contraceptives (n=10). Additionally 8 healthy…
To study whether dipyridamole reduces gastrointestinal absorption of metformin.
To conduct a feasibility study to test 1) whether focused and intensive dual task gait training leads to sustained improvements in complex gait performance. The study will focus hereby on influencing the ability to resist dual task interference, the…
Therefore, the aim of this study will be to assess reproducibility of pseudo-CASL (p-CASL) between 3.0 Tesla MR scanners of two vendors in two medical centers.
Primary Objective: To investigate the spatio-temporal gait parameters in obese and lean subjects to evaluate if there is an effect on the gait pattern after weight loss.Secondary Objectives: - To investigate the effect of weight loss on joint load…
At the moment there is level III evidence for the efficacy of the MIT, mainly for the chronic phase. This study intends to establish a higher level of evidence, both for the chronic phase and for the post-acute phase, when aphasia treatment is…
Examine the effects of a single meal on BAT activation and intrinsic mitochondrial uncoupling in SM in lean and obese individuals, and define the role of the SNS within this response.
Primary Objective: Analyse the behavioural response of individuals with Down's syndrome directly after a painful dental stimulus and compare this with video-analysed behaviour.Secondary Objective(s): 1) Determine which observational scale can…
To replicate and extend the findings of the recent methylphenidate study in which methylphenidate was found to enhance episodic memory performance; To explore whether this effect of methylphenidate is primarily mediated by its dopaminergic action.
The Objective of this study is to validate the new developed sensor fotoplethysmografie (MPA-16), that later can be used to better understand the local vasculature. And determining the feasibility / applicability of this test setup for patients.
The main aim of the current study is to investigate the influence of these SBs on therapeutic progress and outcome. We hypothesize that: 1) SB has a facilitating effect on fear reduction within a therapy session, but that it is also related to…
The proposed study aims to evaluate the recommendations of the guideline regarding the wellbeing of the relatives according to the following questions: 1) To what extent are the recommendations of the guideline adhered to? 2) What is the effect of…