501 results
The primary objective of this study is to determine brain activation in response to olfactory (orthonasal) exposure to different fat levels contained in a ecologically-relevant fat source.
• To assess effects of a single oral dose of 160 and 1500 mg cannabidiol compared to placebo on a specific set of pain modalities• To assess effects of a single oral dose of 160 and 1500 mg cannabidiol compared to placebo on UVB- and capsaicin-…
1. To assess the long-term safety and tolerability of ABBV-8E12 in subjects with early Alzheimer's disease (AD).2. To assess the pharmacokinetics (PK) of ABBV-8E12 in subjects with early AD.The exploratory objectives of this study are:• To…
The main objective of this study is to investigate the possible benefits of micronutrients on irritability as a population trait in children and adolescents between 11 and 17;6 years of age with a high level of irritability. The secondary objectives…
The objective of this study is to demonstrate that use of the Sentinel® Cerebral Protection System significantly reduces the risk of periproceduralstroke (*72 hours) after transcatheter aortic valve replacement (TAVR).
The objective of the current study is to eveluate whether EMDR is effective in reducing PD symptoms.
Primary objective: To investigate changes in biological and psychological markers for patients with an unipolar depressive disorder during treatment.. In specific, we will study the relationship between depressive symptomatology with changes in…
The objective of this study is to assess the performance of the Masimo O3 regional oximeter on somatic tissue oxygenation, under controlled hypoxia. Somatic rSO2 values will be compared with combined arterial and venous blood gas measurements from…
To evaluate whether performing bariatric surgery as outpatient surgery is not inferior to the current treatment based on a combined outcome measure.
To assess the effect of a 6-month regular, low and high dietary sweetness exposure on sweetness preferences, food intake, glucose homeostasis and body weight in healthy adults.
This study aims to further reduce the incidence of a post-ERCP pancreatitis by administrating a single gift antibiotics after the procedure.
This research aims to investigate imaginary rescripting (ImRs) as a 'stand alone' intervention in clients aged eight to twelve years, in which bullying experiences have led to complaint behaviour (emotional problems, depressive complaints…
To assess the impact of CBT on treatment outcome after lumbar spinal fusion surgery in patients with high pain catastrophizing, a two-center randomized controlled trial comparing CBT care to education.
The goal of this study is to assess the recovery of muscle and liver glycogen stores (by ingesting carbohydrates) within 12 hours after exhaustive exercise.
The primary objective of our proposal is to determine embryo development of donated human preimplantation embryos in four different culture media: (1) standard culture medium (control group), (2) culture medium with a uterine-like pH, (3) culture…
The primary objective of this study is to investigate the sequence of segmental contributions in the cervical spine in the long-term follow-up of surgery for CDDD. Specifically, the motion of the cervical spine after ACD and ACDA will be analyzed…
The objective is to validate the NESTORE Platform in relation to three main evaluation criteria: For (1) Feasibility, we will evaluate the validity and the appropriateness of the procedures for the proposed intervention. For (2) Usability and (3)…
The objective of this explorative study is to determine the feasibility of measuring dEMG with a belt in preterm and term born infants during routine caregiving. Feasibility is confirmed when heart rate and respiratory rate reach a predefined level…
The primary objective of this study is to determine which candidate sensors alone or in combination are most correlated with the results from the gold standard technique breath gas analysis and blood lactic acid; and to develop an algorithm that…
This study will evaluate the RESET self-stigma reduction intervention: a face to face group workshop for PLHIV in the Netherlands that aims to reduce HIV-related self-stigma and improve wellbeing, specifically quality of life, self-esteem, resilient…