335 results
The aim of the proposed study is to examine the effectiveness of this new form of attentional bias training as an add-on to treatment-as-usual in facilitating abstinence from alcohol use in patients diagnosed with alcohol dependence. Additionally,…
The main objective of this study is to determine the release profile of the dexamphetamine sustained release tablets in vivo in humans. Depending on the results, the tablets might be candidates for use in the therapy of attention deficit…
The primary objective of this confirmatory study is to confirm the acid neutralisation action of Gaviscon Double Action Liquid versus placebo liquid, within the stomach.
The objective of the LEOPARD-2 trial is to assess the safety of MIPD versus OPD and after that to assess the time to functional recovery of MIPD versus OPD for symptomatic benign, premalignant or malignant peri-ampullary disease.
Safety (Primary) ObjectiveThe primary objective for this study is as follows:- To evaluate the safety and tolerability of cobimetinib in children and young adults, including estimation of the maximum-tolerated dose (MTD) or the maximum administered…
To study the effectiveness of the PhysioDom HDIM intervention in maintaining or improving nutritional status and quality of life. Furthermore, the effects on behavioural determinants, appetite, dietary intake, weight, physical activity, and physical…
In a series of randomized control trials (RCTs) the following hypothesis will be tested: Intranasal administration of oxytocin and vasopressin affect neural and behavioral responses to infant signals and threat to the infant.* Oxytocin and…
The main aim of the study will be to compare the urinary N-nitroso compounds levels after intake of 70 ml of concentrated red beetroot juice containing 400 mg nitrate either with or without supplementation with 1 g vitamin C.
To investigate whether a clinical medication review, focused on the perceived hindering complaints and personal wishes of the patients regarding their medication, improves health-related quality of life of older persons aged 70 years or older using…
Is to identify the incidence and prevalende of PH in premature born infants. In addition we will identify possible risk factors for the development of PH and we want to determine the prognosis and survival of these patients. PrimaryTo determine the…
To main objective is to determine the heat sensation and perception in the great saphenous vein (GSV), anterior accessory saphenous vein (AASV) and/or posterior accessory saphenous vein (PASV).
To compare the effects of exercise therapy on mouth opening using the TheraBite and the DTS in a randomized controlled trial in head and neck cancer patients suffering from trismus.
The aim of the study is to assess the cortical reorganisation after arm amputation using functional connectivity between and within the left and right motor hand areas using resting-state fMRI, and structural connectity using diffusion tensor…
This study aims to identify global and local determinants of HPV vaccine acceptability, HPV vaccine uptake and compliance as well as identify logistics and programmatic issues in each country to offer the HPV vaccine, as a potential cervical cancer…
In this trial we now aim to investigate comprehensively the effect of riboflavin supplementation on the abundance of F. prausnitzii and on other members of the gut microbiota in faeces of healthy volunteers. Additionally we will assess whether…
The aim of this study is to evaluate if direct removal of the urine catheter after an LH (total laparoscopic hysterectomy and laparoscopic supracervical hysterectomy) is associated with similar (or better) outcomes compared to catheter removal the…
The objective of this study is to investigate the effect 8-week OLECOL supplementation on cardiovascular risk markers.
Based on the identified gaps in the evidence underlying the clinical guidelines on non-specific low back pain of the Dutch College of GPs and the recent findings of the Australian PACE study the objectives of the present study are: 1. What is the…
Comparing the additional effects of UVB irradiation to oral vitamin D supplementation on well-being and quality of life in psycho-geriatric nursing home residents.
The primary objective of this study is:After 3 treatment cycles in healthy female subjects between the ages of 18 and 50 years (inclusive): To estimate the effect of the ENG-E2 vaginal ring compared with the LNG-EE COC on hemostatic parameters that…