329 results
The main objective of this study is to analyze the effect of early (12 weeks corrected age) versus late (17 weeks corrected age) introduction of complementary food (weaning) on the prevalence of obesity at the age of 2 years in preterm infants.…
The main objective is to compare growth and body composition of late preterm infants at 6 months corrected age, fed either an isocaloric, protein- and mineral-enriched ('postdischarge') formula (PDF) or standard term formula (TF) between…
The aim of this project is to maintain quality of life and improve cancer related outcome by preventing therapy-related toxicity (and ensuing unplanned hospital admission and /or discontinuation of chemotherapy) in cancer patients treated with…
In this study we want to validate a risk score for chronic dizziness with persistent impairment in older dizzy patients in general practice. Furthermore, we want to investigate the effectiveness of a risk factor-guided, i.e. a prognosis-oriented,…
The primary aim of the study is to establish the cross-sectional validity of three different measurement instruments for central sensitization, including the Dutch Central Sensitization Inventory and two test to measure pain inhibition: heterotopic…
In this sub-study we will explore whether the inhibitory effects of conditioned stimuli depent on the subjective experience of pain. Furthermore, we will explore the time-frame of these inhibitory effects.
The primary goal is to investigate the responsiveness of the coordination measurement in patients with low back pain.
We hypothesize that formerly pre-eclamptic women have persistently increased angiotensin II sensitivity, sodium sensitivity, insulin resistance and sympathetic nerve activity together initially leading to susceptibility for early renal disease and…
The main objectie of the study is to map the developmental trajectory of processing perceptual and social information in infants using fNIRS. In addition, with the measurement in 5 month-old children we aim to replicate previous research. The…
We hypothesize that perioperative ketamine will reduce cognitive decline in postoperative patients, in line with its analgesic and anti-inflammatory properties. There are no previous data available on the effect of ketamine on postoperative…
The objective of this study is to explore the effects of spinal anesthesia on hemodynamic parameters of fluid status, especially vena cava inferior diameter and collapsibility. TFurthermore, the correlation between vena cava inferior collapsibility…
The primary objective of this Randomised Controlled Trial (RCT) is to evaluate the efficacy of DRG stimulation with the Axium® SCS system as compared to CMM in terms of pain relief. Efficacy will be assessed by comparing the percentage of subjects…
Primary Objectives:(1) Objective: To compare the overall survival (OS) in subjects with R/M HNSCC treated with pembrolizumab compared to standard treatment.Secondary Objectives:PD-L1 Positive Population:(1) Objective: To compare Overall Survival (OS…
Researching if the injection of PRP with patients suffering from discogenic low back problems with or without anular tear, without modic has significant beneficial effects on pain and functionality.
We will investigate the relationship between this permeability measure and (i) cognitive performance and (ii) the status of MRI visible cerebrovascular pathology (i.e. white matter hyperintensities, lacunar infarctions, microbleeds) in the most…
The general aim of this present study is to investigate whether blockade of the saphenous nerve can provide the same degree of analgesia postoperatively for ACLS as a femoral nerve block without resulting motor blockade enhancing shortening of…
The primary objective of this project is to evaluate the primary and secondary technique effectiveness of IRE for centrally located colorectal liver metastases that are neither amenable for resection nor for other local ablation methods due to the…
RO7009789 and atezolizumab are experimental drugs that are being investigated by F. Hoffmann La Roche Ltd for the treatment of locally advanced and / or metastatic solid tumors.
1. To study the short- and long-term effect of different target PaO2's on circulatory status, organ dysfunction and outcome.2. To study underlying mechanisms of hyperoxia by determining differences in oxidative stress response between the…
To investigate the effect of variations in the pouch shape and size in RYGB on weightreduction.