117 results
The primary objective is acquiring insights in the development of BOS in patients after human lung transplantation in an early phase of the disease which can be used to improve immunotherapeutic handling in order to prevent or delay the onset of BOS…
zie bovenstaand
The current project aims first to examine whether IPT produces outcomes that are superior to the comprehensive treatments already available ('care as usual'). Primary outcomes include parenting behavior and the quality of the parent-child…
To determine the effects of feedback regarding patient progress on patient outcome and number of treatment sessions. Questions are::1, Is monitoring with feedback to therapists more (cost-)effective than monitoring without feedback; 2, is feedback…
the investigation and evaluation of certain serummarkers for inflammation and tumoractivity during the followup of colorectal neoplasms, and the applicability of these markers during the followup of these patients or the evaluation of the effect of…
In previous studies we have identified specific receptor and surface protein expression profiles on neutrophils. Some of these profiles point at partially refractory neutrophils. In the current NERTHUS study we have seen that circulating neutrophils…
This study investigates the effects of monitoring patient progress and the development of the therapeutic alliance from patients perspective and providing infromation to both, patients and therapists.
The following research questions are answered in the research. I. To what extent does filling out an Implementation Intentions form influence the compliance when using `the online bewegingscoach'? II To what extent can intention be explained by…
The study is an explorative study of the effects that might occur in conversations between a client and a therapist, the latter intervening as permisive as possible. Its goal is to study the effects in the client of permissive intyerventions by the…
The objectives of this research is to asess the family-intervention Triple P on:1) effectiveness in terms of (-) decrease of behavioural- and emotionel problems of the child (SDQ)2) effectiveness in terms of (-) improvement of the competence of the…
·implementation objective(s)/research question(s): The main aim is to compare the effectiveness and costs of the implementation of elective single embryo transfer (eSET) in in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI),…
The aims of this proposal are to show that, additional to a normal daily food intake, the intake of carbohydrate and protein during and post-exercise increases muscle protein synthesis. Second, that the intake of carbohydrate and protein during…
To study the effect of a vitamin K-containing food supplement on osteocalcin carboxylation in healthy children between 6 and 10 years of age in the Netherlands.
Secondary HPT is common in people with CKD. Patients with secondary HPT often have high PTH levels and may develop large parathyroid glands in the neck. Patients with secondary HPT may have bone disease (osteodystrophy). This bone disease may cause…
Aims of the study:1) To obtain pharmacokinetic parameters of S(+)-ketamine;2) To study the pharmacodynamic effects of intravenous S(+)-ketamine on experimental pain;
1. The central hypothesis of this study is that genetic polymorphisms in drug metabolising enzymes and regulators of enzyme expression may predispose to ATDH. We propose to evaluate the presence of genetic polymorphisms among TB patients in…
1. What is the effect of a clinical oral dose of acetazolamide on the isocapnic hypoxic response (IHR), i.e. an exposure to hypoxia (end-tidal PO2 ~ 5.8 kPa) during 30 min? Does the agent increase the IHR as would be expected from the state of…
To evaluate detection thresholds, functioning of the HPA-axis and risk of chronic pain in children of 5-years of age who experienced pain and received morphine in neonatal period in compare with children of 5-years of age who experienced pain…
Aim of the present study is to determine · whether and to what extent nadroparin is excreted by CVVH · whether the drug accumulates during CVVH as measured by anti-Xa activity and endogenous thrombine potential (ETP)· whether clearance of nadroparin…
The objective of this study is to determine the influence of ambient noises upon the characteristics of fMRI signals that are of relevance in connectivity measurements.The study will focus on the influence on the statistical properties of measurable…