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(1) To study the efficacy of AET for improving activities and QoL in patients with ALS. (2) To identify generic and disease-specific determinants of effects. (3) To obtain insight into patients* , partners* and professionals' expectations of…
To determine the incidence of hypopituitarism in patients after SAHTo identify neurological parameters that predict hypopituitarism after SAHTo determine the value of a Ghrelin test shortly after SAH, to identify subjects with GHD.To determine the…
The aim of the study is to evaluate the effectiveness of an activity stimulation program on performance of mobility and lifestyle in children with cerebral palsy, in comparison with regular paediatric physiotherapy.
1) to investigate cognitive functioning in lacunar infarct patients with and without periventricular white matter lesions; 2) to identify predictors for cognitive dysfunction in lacunar infarct patients.
The objective is to determine whether ITB Therapy is more effective than oral anti-spasticity agents in reducing the spasticity.
The objectives of this study are to examine: (1) the long-term safety and efficacy of alemtuzumab in multiple sclerosis (MS) patients who received alemtuzumab during prior Genzyme-sponsored studies including CAMMS223, CAMMS323, or CAMMS32400507 (…
To make laquinimod 0.6 mg available for all subjects who completed the placebo-controlled MS-LAQ-301 study according to the protocol and to evaluate the long-term safety, tolerability and effect on disease course of daily oral laquinimod 0.6 mg in…
1) To evaluate the efficacy of knee-ankle-foot orthoses (worn by night) in preventing a decrease of range of motion to ankle dorsiflexion in children with cerebral palsy (Clinical part). 2) To evaluate the effect of night-worn knee-ankle-foot…
At the moment there is level III evidence for the efficacy of the MIT, mainly for the chronic phase. This study intends to establish a higher level of evidence, both for the chronic phase and for the post-acute phase, when aphasia treatment is…
The first goal of the present study is to elucidate the network topology of the MTL on both large-scale and micro-scale levels with the aim of further understanding epilepsy related changes to the network structure. Additionally we will also use the…
- To investigate whether the effect of early-start rasagiline treatment (according to the ADAGIO study protocol) provided long term benefits over delayed-start.- To investigate the long-term effects of rasagiline in PD subjects who participated in…
In this study we aim to examine the relationship between certain potential risk factors and the development of Parkinson Disease: environmental exposure to pesticides, exposure to extremely low frequency electromagnetic fields, and the role of…
The general objective is to validate and assess the clinical and economic added-value of a) innovative diagnostic tests developed in WP1 (PET tracers), WP2 (ultra high field MRI) and WP3 (CSF), and b) other emerging diagnostic tests for Alzheimer…
(1) To asses the influence of P-gp function at the BBB on flumazenil binding to the GABAA-receptor in pharmacoresistant patients with temporal lobe epilepsy (TLE), using PET and [11C]flumazenil as a ligand and tariquidar as P-gp blocker. (2) If we…
To evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic LRS.
To sess the relationship between cerebral perfusion and clinical findings (neurological and neuropsychological) in patients with sickle cell disease.To compare iamging fincdings in children with and without sickle cell disease.
The aims of the study are 1) to upgrade an existing GA protocol based on inertial system(developed at the INAIL Prostheses Centre in collaboration with the University of Bologna) in terms offinding out which calibration procedures result suitable to…
OBJECTIVES: -to assess the usefulness of DA-phMRI (task related fMRI, steady state fMRI and ASL based phMRI) in assessing amphetamine induced DA-neurotoxicity when compared to DAT SPECT.-to assess which MRI technique (task related fMRI, steady state…
OBJECTIVESPrimary ObjectiveThe primary objective is to evaluate the efficacy, safety, and tolerability of 800 and 1,200 mg/day of carisbamate compared with placebo in reducing the average daily pain in subjects with diabetic peripheral neuropathy (…
Evaluate and compare the efficacy and safety of escalating doses of BF2.649 and BF2.649 add on Modafinil on cataplexy attacks.Evaluate the additive/synergistic effect of the combination of BF2.649 and Modafinil on excessive daytime sleepiness (EDS…