38 results
We hypothesize that the fertility enhancing effect of OSCM during HSGs is also present during THL.
We hypothesize that CTC detection through diagnostic leukapheresis improves the detection rate among ER+, N+ primary breast cancer who have received 5 years of adjuvant endocrine therapy and will be a promising technique for risk classification in…
Postoperative NRS pain scores in the breast after BCS are lower in women who receive a preoperative PECS II block than in women who receive a sham block.
The overall study aim is to determine the efficacy rate of complete ablation for the most promising types of thermal ablation (RFA, MWA or CA) technique for patients with early stage breast cancer (cT1N0M0) without an extensive component of DCIS (…
To study if a blended personalized periconception lifestyle care approach aimed at women with a high risk for pregnancy complications who are contemplating pregnancy or already pregnant (*12 weeks) can significantly reduce Lifestyle Risk Score.
To determine the feasibility of additional flushing of the fallopian tubes with Lipiodol after tubal testing with methylene-blue during THL.
Primary Objective: The aim of this study is to compare if an online consultation with diagnostic testing during a fertility workup, is as effective as a regular consultation in terms of patient centeredness, shared decision making and costs.
1. To compare pembrolizumab plus enzalutamide plus ADT versus placebo plus enzalutamide plus ADT with respect to radiographic progression free survival (rPFS)2. To compare pembrolizumab plus enzalutamide plus ADT versus placebp plus enzalutamide…
Primary objective: to study the (cost) effectiveness of applying the 4DryField barrier on the uterine scar after a caesarean delivery, in the prevention of adhesions, niche development and related gynecological symptoms. Secondary objectives: to…
In this pilot study will focus on the question whether it is possible to detect and distinguish specific immune cells which are previously found in endometriotic tissue, in , macroscopically non-affected peritoneum, peritoneal fluid, peripheral…
Investigation of maintenance of erectile function after MR-guided radiotherapy with neurovascular sparing in patients with localized prostate cancer.
Primary Objective: To study the feasibility of Velocity Selective Arterial Spin Labeling as a non-invasive technique for breast cancer screening by comparing image quality with DCE-MRI.Secondary Objectives: Comparing tumor characteristics and…
The main goal of this study is to analyse the influence of the menstrual cycle on NK cell receptor variability.
The current research is focused on finding a method that is able to better stratify the patients. A possible method could be to study PSA in more detail, specifically the modifications which are present on the protein. One of these modifications is…
The aim of this study is to evaluate the difference in the fraction of patients that have disease progression within 6 months after applying 177Lu-PSMA RLT in patients with low volume, hormone sensitive metastatic prostate cancer. Ultimately, the…
This study aims to create an indication of the effect size during and after adherence to the low FODMAP diet to calculate a sample size for a future RCT on this subject.
Patients will be included in 3 prospective cohorts, cohort A, B, C and 1 retrospective cohort, cohort 0. Cohort A: The primary objective of cohort A is to show that by implementing a standard infrastructure all newly diagnosed girls with cancer (or…
The primary objective of this study is to investigate whether usual care combined with CBT improves QoL in patients undergoing surgery for endometriosis compared to usual care only. Secondary objectives are to investigate whether pain intensity,…
- To compare the effect of capivasertib + abiraterone relative to placebo + abiraterone by assessment of radiographic progression-free survival PFS) in patients with PTEN-deficient mHSPC.
This protocol describes a framework that will be used to create multiple studies, which are based on the secondary objectives. The outcomes of the studies together will provide more insight in the primary objective. Primary Objective: Investigate…