87 results
Aim of this pilot study is to determine which intervention groups are feasible in a larger trial which aims to a compare postoperative pain and complication rates in moderate versus deep neuromuscular blockade, and normal versus low intra-abdominal…
The aim of this pilot study is to assess the effect of low intensity mastication training in patients with a mitochondrial disease on masticatory performance, efficacy, endurance, bite force and the feasibility of this training .
Primary objectives: 1) To investigate the effect of cold exposure on the glycaemic and insulinaemic responses to an oral glucose load in healthy male adults. 2) To investigate the effect of cold exposure on the glycaemic and insulinaemic responses…
The primary objective of the current intervention trial is to evaluate in elderly men and women the effect of a 16-week soy treatment on gray matter cerebral blood flow, as quantified by the non-invasive gold standard magnetic resonance imaging (MRI…
To determine the natural variation of HbA1c in a group of older volunteers without DM during a period of 2 years.
The primary objective of this study is to determine the efficacy of a predefined vitamin D dosing regimen on the prevalence of vitamin D insufficiency in MM patients. Secondary objectives are to detect the influence of several variables (age, gender…
To study the effect of WF Fiber on insulin resistance and (continuous) glucose metabolism and potential underlying mechanisms, body weight and waist circumference, microbiota composition and fasting GLP1/PYY/SCFA, in subjects with pre-diabetes.
The main objective of the study is to determine the albuminuria lowering effect of the GLP1-RA exenetide, SGLT-2 inhibitor dapagliflozin and their combination in patients with type 2 diabetes and micro- or macroalbuminuria.Secondary objectives are…
To examine whether L-arabinose addition to a sucrose drink will lower glycaemic and insulinemic responses in people at increased risk of developing type II diabetes.
The primary objective is to evaluate in the two targeted populations (i.e. CD and self-reported NCGS subjects):1) the safety profile of BL NCC 2705 2) the gastro-intestinal (GI) tolerability of BL NCC 2705
Primary Objective: * Study the relationship between the pre-transplant plasma oxalic acid level and the risk of oxalate deposition in for cause renal transplant biopsies within 6 months after renal transplantation. Secondary Objective(s): * Track…
The main goal of this study is to investigate whether (postprandial) intestinal acetate production may be related to plasma acetate, insulin secretion/sensitivity and the CNS regulation of food intake and whether these findings differ between people…
1. To establish optimized and standardized approaches for the isolation and characterization of BOECs in control and diabetic patients.2. To test whether the phenotype of BOECs cultured from blood of diabetic patients are significantly different…
Primary objectives:* To assess telmisartan target (i.e. receptor) specific binding in vivo* To assess receptor occupancy of telmisartan in vivo* To determine optimal scanning time in vivoSecondary objective:* To explore the effect of telmisartan on…
The main objective is to validate serum calcification propensity as a read-out for vascular calcification and the secondary objective is to identify determinants of vascular calcification (progression).
The primary objective of the proposed study is to evaluate the effect of the high dose or L-arginine (3.0 gram) and a lower dose of L-arginine (1.5 gram) compared with a placebo supplement on postprandial vascular function, assessed by brachial…
To like or not to like: On negotiating taste in children of families with lower socioeconomic status
The primary objective of the study is to map the existing (range of) implicit and explicit associations between (un)healthy, (not) tasty and (dis)liking of foods in low-SES families (parents and children). The secondary objective is to unravel if…
The objective of this study is to evaluate the safety of the PlenSat Digestible Balloons.
The objective of this pilot study is to investigate the efficiency of a glucose monitor device placed in a tear fluid of human eye to measure glucose for up to 6 hours and its correlation to blood glucose values. Additionally, more information will…
Primary Objective:Determine the relevance, feasibility, reliability (test-retest, inter- and intra-rater) and validity of a selected set of outcome measures in children with mitochondrial encephalopathy. Secondary Objective: Determine in- and…