41 results
Are changes in cognitive functioning related to structural changes in the brain in patients with type 1 diabetes mellitus. How are these changes related to diabetic complications like duration of chronic hypoglycaemia, disease duration and presence…
The objective of this study is to develop a resistance training intervention that improves mobility and quality of life in diabetic patients. It is also our intension to achieve a better understanding of the relation between diabetic neuropathy and…
1) To assess whether galactosemia women with ovarian failure are able to produce estradiol after exogenous (normally bioactive) FSH and LH gift 2) To characterize FSH glycan structures
To optimize a safe five-day intensive intravenous insulin treatment post stroke and to assess glucose profiles in patients with stroke and HG on admission, receiving standard continues enteral tube feeding.
To quantify the impact of outpatient nurse-led prevention clinics on the risk of future clinical events in patients with symptomatic coronary artery disease.
The goal of this study is examining the acute effects of insulin on microcirculation in hypertensive insulinresistant subjects and investigate if angiotensine II influences these effects. Amendement: The goal of the amendement is to exame the…
Investigate effect of IF on insulin resistance and possible role acylcarinitin profiles and glycolipids
The application of CGMS offers novel possibilities to define the impact of different exercise parameters like exercise duration, frequency and intensity on glycemic control in type 2 diabetes patients. In addition we are interested in the impact on…
The main question is: does an ethnic specific cultural approach, including an ethnic specific education programme and individual guidance by a bicultural educator as part of the multidisciplinary team, has a beneficial effect on glycaemic control in…
To study the effect of a vitamin K-containing food supplement on osteocalcin carboxylation in healthy children between 6 and 10 years of age in the Netherlands.
To examine the safety, tolerability, and effect on glucose metabolism of metformin treatment in non-diabetic patients with TIA or minor ischemic stroke and impaired glucose tolerance.
Part 1 of the study has two objectives. Firstly, we will study the safety and tolerability of the drug after the administration of single ascending oral doses of the drug. Secondly we will study the pharmacokinetics and pharmacodynamics. This means…
Evaluation of the incidence of liver enzyme abnormalities and hepatic steatosis in all type 2 diabetes mellitus patients (about n=1500) treated at the outpatient clinic internal medicine of the St Lucas Andreas Hospital
Is long-term PPI-use associated with low vitamin B12 levels in old age?
We found a prevalence of 6% sensitization in patients with a possible food allergy. The aim of this study is to investigate if sensitization to lupine flour in atopic patients has clinical relevance. Additionally, we want to investigate if cross-…
The Municipal Health Service The Hague and the LUMC are planning to conduct a study similar to the one in Pune in The Hague. In the start-up phase of this study we are preparing a pilot study in which we will study anthropometry and insulin…
1. to investigate whether the known chronic inflammatory and hyperoxidative state in patients with severely increased LDL is associated with dysfunctional HDL.2. to investigate whether CVD in FH is associated with dysfunctional HDL.
The primary objective of this study is to investigate the peri-operative accuracy and safety of the RT-CGMS in cardiac surgical patients.The secondary objective is to identify and define possible factors interfering with reliable and adequate…
The general aim of this pilot study is to assess the feasibility of using the Vincent 50 foot scanner for the acquisition, diagnosis, and referral of foot problems in the home environment in diabetic patients at high risk of ulceration.Specific aims…
Aim of the study is to answer the following questions:What is the influence of drinking different kinds of volumes on energy expenditure?What is the influence of drinking solutions with different osmolarities on the energy expenditure?Are changes in…